{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:48:51Z","timestamp":1777927731755,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1995,3,1]],"date-time":"1995-03-01T00:00:00Z","timestamp":794016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[1995,3]]},"abstract":"<jats:p>Forty-two Tanzanian patients with genital warts were treated with 0.5% podophyllotoxin solution (Wartec) for 3 days. Thirteen patients (30.9%) were cured and a further 7 patients (16.7%) had more than 50% of lesions cleared at 6 weeks, while 19 patients were resistant to treatment. Three patients had a recurrence of lesions after an initial response. Thirty-three patients were tested for serological evidence of infection with human immunodeficiency virus (HIV) and 15 (45.5%) patients were shown to be HIV-1 antibody positive. The response to treatment was analysed in relation to HIV antibody status. The cure rate was significantly higher in HIV seronegative patients (8\/18=44.4%) compared to HIV seropositive patients (1\/15=6.7%) (P=0.018). We conclude that podophyllotoxin treatment provides a useful non-hospital based treatment for genital warts, but HIV infection appears to contribute to the failure of treatment for genital warts.<\/jats:p>","DOI":"10.1177\/095646249500600210","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T17:38:28Z","timestamp":1484329108000},"page":"114-116","source":"Crossref","is-referenced-by-count":11,"title":["Response to Podophyllotoxin Treatment of Genital Warts in Relation to HIV-1 Infection among Patients in Dar Es Salaam, Tanzania"],"prefix":"10.1177","volume":"6","author":[{"given":"C D S","family":"Kilewo","sequence":"first","affiliation":[{"name":"Department of Obstetrics\/Gynaecology, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W K","family":"Urassa","sequence":"additional","affiliation":[{"name":"Department of Microbiology\/Immunology, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Pallangyo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Mhalu","sequence":"additional","affiliation":[{"name":"Department of Microbiology\/Immunology, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Biberfeld","sequence":"additional","affiliation":[{"name":"Swedish Institute for Infectious Disease Control and Karolinska Institute, 105 21 Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Wigzell","sequence":"additional","affiliation":[{"name":"Swedish Institute for Infectious Disease Control and Karolinska Institute, 105 21 Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1995,3,1]]},"reference":[{"key":"bibr1-095646249500600210","first-page":"1","volume":"33","author":"Kirchner H.","year":"1986","journal-title":"Prog Med Virol"},{"key":"bibr2-095646249500600210","doi-asserted-by":"publisher","DOI":"10.1016\/0166-3542(89)90022-3"},{"key":"bibr3-095646249500600210","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1989.tb00504.x"},{"key":"bibr4-095646249500600210","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91072-5"},{"key":"bibr5-095646249500600210","first-page":"396","volume":"62","author":"Avgerinou G","year":"1986","journal-title":"Genitourin Med"},{"key":"bibr6-095646249500600210","first-page":"289","volume-title":"GPVI\u2014Genital Papilloma Virus Infection\u2014A survey for the clinician","author":"Jablonska S","year":"1989"},{"key":"bibr7-095646249500600210","first-page":"1","volume":"64","author":"Kreiss J","year":"1988","journal-title":"Genitourin Med"},{"key":"bibr8-095646249500600210","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-198906000-00007"},{"key":"bibr9-095646249500600210","first-page":"1002","volume":"3","author":"Nsubuga P","year":"1990","journal-title":"J Acquir Immune Defic Syndr"},{"key":"bibr10-095646249500600210","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/163.2.233"},{"key":"bibr11-095646249500600210","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-198107000-00002"},{"key":"bibr12-095646249500600210","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-198707000-00003"},{"key":"bibr13-095646249500600210","first-page":"302","volume":"2","author":"Pickering RW.","year":"1989","journal-title":"Br J Sexual Med"},{"key":"bibr14-095646249500600210","first-page":"105","volume":"70","author":"von Krogh G","year":"1994","journal-title":"Genitourin Med"}],"container-title":["International Journal of STD &amp; 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