{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T13:00:02Z","timestamp":1780750802752,"version":"3.54.1"},"reference-count":89,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hist Psychiatry"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>A century ago, malaria therapy for general paralysis of the insane was a celebrated Nobel Prize-winning psychiatric treatment widely used across the globe. However, in recent years, its legacy has come under increasing scrutiny, with some historians and physicians questioning the claims of it being an effective treatment. This paper, utilizing published accounts and medical record archives, describes malaria therapy for neurosyphilis as conducted by psychiatrist, Reginald Ellery at Victoria\u2019s Mont Park Hospital for the Insane, 1927\u20131928. It also evaluates Ellery\u2019s claims about malaria therapy\u2019s effectiveness. This research delineates several clinical and research-related factors \u2013 such as diagnostic drift, adjunct interventions, and healthy-patient selection \u2013 that likely contributed to an overestimation of malaria therapy\u2019s effectiveness. Additionally, it demonstrates that patient outcomes as reported in the medical records are notably less positive than described by Ellery in his published accounts. Consequentially, the findings of this study do not support the claims of malaria being an effective treatment for neurosyphilis.<\/jats:p>","DOI":"10.1177\/0957154x251403921","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:10:50Z","timestamp":1767165050000},"page":"135-158","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Malaria therapy for neurosyphilis at Mont Park Hospital for the insane in Australia, 1927\u20131928"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3634-234X","authenticated-orcid":false,"given":"Alison","family":"Clayton","sequence":"first","affiliation":[{"name":"University of Melbourne, Parkville, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,30]]},"reference":[{"key":"e_1_3_4_4_1","unstructured":"CID: Coronial Inquests Deposition Files VPRS 24\/P0000."},{"key":"e_1_3_4_5_1","unstructured":"MPADR: Mont Park Admission-Discharge Register VPRS 17872\/P0001\/Unit 2."},{"key":"e_1_3_4_6_1","unstructured":"MPCF: Mont Park Correspondence files 1928\u2013 1931 VPRS 7532\/P000\/Units 3 4."},{"key":"e_1_3_4_7_1","unstructured":"MPPCN: Mont Park Mental Hospital Patient Clinical Notes VPRS 18124\/P0001\/Unit 2."},{"key":"e_1_3_4_8_1","unstructured":"MPPMR: Mont Park Post-Mortem Register VPRS 07434\/P0001\/Unit 1 2."},{"key":"e_1_3_4_9_1","unstructured":"MPVBR: Mont Park Voluntary Boarder Admission-Discharge Register VPRS 17871\/P0001\/Unit 1."},{"key":"e_1_3_5_3_1","volume-title":"Therapeutic Malaria: A Personal Review","author":"EM\/SLV","year":"1929","unstructured":"EM\/SLV (1929a) Therapeutic Malaria: A Personal Review. 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