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A total of twenty animals were used, each receiving three standardized dorsal burns of equal size, treated with either a simple dressing (negative control), a nanocellulose membrane without silver, or a nanocellulose membrane containing silver. Healing was monitored through macroscopic and microscopic analyses performed on days 3, 7, 14, and 30 after the induction of the burns. The findings demonstrated that nanocellulose membranes effectively promoted tissue repair and skin regeneration, with evidence of fibroblast activity, collagen deposition, and neovascularization throughout the healing process. The incorporation of silver nanoparticles showed potential to enhance early wound contraction, although all groups achieved complete re-epithelialization by the end of the experimental period. While the addition of silver may contribute to antimicrobial protection and early tissue response, further studies are required to confirm its role in accelerating the healing process and to better elucidate its mechanisms of action. Overall, pinus sp. nanocellulose membranes represent a safe and effective alternative for the treatment of burns, supporting their potential application in clinical practice.<\/jats:p>","DOI":"10.1177\/09592989261453731","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:28:06Z","timestamp":1785817686000},"page":"191-199","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Softwood nanocellulose\u2013silver nanoparticle membranes for burn wound healing in rabbits"],"prefix":"10.1177","volume":"37","author":[{"given":"Leticia G.","family":"de Gutierrez","sequence":"first","affiliation":[{"name":"Postgraduate Program in Veterinary Medicine, Federal University of Campina Grande, Patos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine C.","family":"Claro","sequence":"additional","affiliation":[{"name":"Graduate Program in Materials Science and Engineering\u2014PIPE, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4405-293X","authenticated-orcid":false,"given":"Washington L.E.","family":"Magalh\u00e3es","sequence":"additional","affiliation":[{"name":"EMBRAPA Florestas, Colombo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0128-6488","authenticated-orcid":false,"given":"Marcelo J.C.","family":"de S\u00e1","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Veterinary Medicine, Federal University of Campina Grande, Patos, Brazil"},{"name":"Department of Veterinary Medicine, Federal University of Campina Grande, Patos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6161-4626","authenticated-orcid":false,"given":"Gabriel Goetten","family":"de Lima","sequence":"additional","affiliation":[{"name":"PRISM Research Institute, Technological University of the Shannon, Midlands Midwest, Athlone, Ireland"},{"name":"Postgraduate Program in Mechanical and Materials Engineering, Research Center for Rheology and Non-Newtonian Fluids, Federal University of Technology-Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,3]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2023.02.058"},{"key":"e_1_3_3_3_2","first-page":"86","article-title":"Burn Care Unit of S\u00e3o Paulo Federal University: an epidemiological profile","volume":"30","author":"Dias LDF","year":"2015","unstructured":"Dias LDF, Oliveira AF, Juliano Y, et al. 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