{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:28:46Z","timestamp":1777667326473,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2011,1,19]],"date-time":"2011-01-19T00:00:00Z","timestamp":1295395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p>Neonatal hemochromatosis (NH) is a rare disease of iron metabolism that starts at intrauterine period causing liver failure and extrahepatic siderozis. The etiology of NH has not been understood exactly, yet it is accepted that a maternofetal alloimmune disorder that leads to liver failure in fetus causes the illness. The prognosis of NH is generally bad and death is inevitable if left untreated. The efficiency of chelation\u2013antioxidant coctail used in medical treatment is between 10% and 20% and these patients frequently need liver transplantation. In our study, we presented four newborn cases diagnosed as NH and treated medically. Of the four patients, one died of pulmonary hemorrhage and another died of multiorgan failure in the first week of hospitalization. The other two patients' clinical status and laboratory parameters recovered with medical treatment. However, since liver transplantation was not carried out, one of these patients died at the age of two and a half months and the other at eighth month due to sepsis. In this study, we would like to emphasize the importance of early liver transplantation in patients recovered with medical treatment.<\/jats:p>","DOI":"10.1177\/0960327110396534","type":"journal-article","created":{"date-parts":[[2011,1,19]],"date-time":"2011-01-19T20:59:31Z","timestamp":1295470771000},"page":"1728-1734","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Therapeutic management of neonatal hemochromatosis: Report of four cases and literature review"],"prefix":"10.1177","volume":"30","author":[{"given":"Ali","family":"Annag\u00fcr","sequence":"first","affiliation":[{"name":"Division of Neonatology, Selcuk University Meram Medical Faculty, Konya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00fcseyin","family":"Altunhan","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Selcuk University Meram Medical Faculty, Konya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan Ali","family":"Y\u00fcksekkaya","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, Selcuk University Meram Medical Faculty, Konya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahmi","family":"\u00d6rs","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Selcuk University Meram Medical Faculty, Konya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,1,19]]},"reference":[{"key":"bibr1-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(03)00050-5"},{"key":"bibr2-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-985069"},{"key":"bibr3-0960327110396534","first-page":"39","volume":"37","author":"Cottier H","year":"1957","journal-title":"Schweiz Med Wochenschr"},{"key":"bibr4-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.4.960"},{"key":"bibr5-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e328336ebe1"},{"key":"bibr6-0960327110396534","first-page":"1","author":"Boyd RL","year":"2008","journal-title":"Emedicine"},{"key":"bibr7-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318046772f"},{"key":"bibr8-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1097\/ANC.0b013e31819ac020"},{"key":"bibr9-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3107"},{"issue":"3","key":"bibr10-0960327110396534","first-page":"328","volume":"34","author":"Shneider BL","year":"2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"bibr11-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181d24517"},{"key":"bibr12-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0908"},{"key":"bibr13-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.38.9.599"},{"key":"bibr14-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17356-X"},{"key":"bibr15-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21129"},{"key":"bibr16-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0784"},{"key":"bibr17-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1006\/bcmd.2002.0580"},{"key":"bibr18-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1097\/01.MPG.0000162004.44971.92"},{"key":"bibr19-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2005.00357.x"},{"key":"bibr20-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20497"},{"key":"bibr21-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-199610000-00013"},{"key":"bibr22-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2002.tb03341.x"},{"key":"bibr23-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1186\/1824-7288-36-38"},{"key":"bibr24-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199801000-00015"},{"key":"bibr25-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20461"},{"key":"bibr26-0960327110396534","first-page":"12","volume":"1725","author":"Williams H","year":"2006","journal-title":"Liver Transpl"},{"key":"bibr27-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1097\/01.MPG.0000148837.52624.48"},{"key":"bibr28-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2004.05.021"},{"key":"bibr29-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20541"},{"key":"bibr30-0960327110396534","doi-asserted-by":"publisher","DOI":"10.1136\/fn.88.2.F124"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327110396534","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0960327110396534","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327110396534","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:46:15Z","timestamp":1777448775000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0960327110396534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,19]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["10.1177\/0960327110396534"],"URL":"https:\/\/doi.org\/10.1177\/0960327110396534","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1,19]]}}}