{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:29:14Z","timestamp":1777667354501,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2011,3,22]],"date-time":"2011-03-22T00:00:00Z","timestamp":1300752000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:p>The aim of this retrospective epidemiological study was to investigate the demographical, etiological and clinical characteristics of acute drug poisonings in Iasi County, Romania. All patients were referred and admitted in the Toxicology Clinic of \u201cSf. Ioan\u201d Emergency Clinic Hospital Iasi, Romania. Between 2003 and 2009, 811 cases of acute drug poisonings were recorded, counting for 28.43% from the total number of poisonings. The majority of these poisonings resulted in mild (51.94%) and medium (28.35%) clinical forms, while 19.71% were coma situations. In all, 63.51% of patients originated from urban areas, 39.94% were unemployed and the patients were predominantly women (66.46%). A high percentage (97.27%) were suicide attempts, using only one type of drug (65.88%) and the 21\u201330 years group (29.8%) records the highest incidence, for both women and men. The most frequently involved drugs were benzodiazepines 13.69%, anticonvulsive drugs 8.63%, barbiturates 8.51% and cardiovascular drugs 5.92%. Drugs combinations were recorded in 32.92% of cases and 1.2% were combinations between drugs and other substances. Mortality was the outcome in 0.3% of the total registered number of acute drug poisonings. This study underlines that in order to provide a proper management of these situations, a Regional Poison Information Center is absolutely necessary.<\/jats:p>","DOI":"10.1177\/0960327111403172","type":"journal-article","created":{"date-parts":[[2011,3,22]],"date-time":"2011-03-22T21:09:46Z","timestamp":1300828186000},"page":"1896-1903","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Epidemiology of acute drug poisoning in a tertiary center from Iasi County, Romania"],"prefix":"10.1177","volume":"30","author":[{"given":"Victorita","family":"Sorodoc","sequence":"first","affiliation":[{"name":"\u201cSf. Ioan\u201d Emergency Clinic Hospital, Internal Medicine Department, Faculty of Medicine, \u201cGr. T. Popa\u201d University of Medicine and Pharmacy, Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina M","family":"Jaba","sequence":"additional","affiliation":[{"name":"Pharmacology \u2013 Toxicology Department, Faculty of Medicine, \u201cGr. T. Popa\u201d University of Medicine and Pharmacy, Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalina","family":"Lionte","sequence":"additional","affiliation":[{"name":"\u201cSf. Ioan\u201d Emergency Clinic Hospital, Internal Medicine Department, Faculty of Medicine, \u201cGr. T. Popa\u201d University of Medicine and Pharmacy, Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ostin C","family":"Mungiu","sequence":"additional","affiliation":[{"name":"Pharmacology \u2013 Toxicology Department, Faculty of Medicine, \u201cGr. T. Popa\u201d University of Medicine and Pharmacy, Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurentiu","family":"Sorodoc","sequence":"additional","affiliation":[{"name":"\u201cSf. Ioan\u201d Emergency Clinic Hospital, Internal Medicine Department, Faculty of Medicine, \u201cGr. T. Popa\u201d University of Medicine and Pharmacy, Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,3,22]]},"reference":[{"key":"bibr1-0960327111403172","doi-asserted-by":"publisher","DOI":"10.3109\/15563650903438566"},{"key":"bibr2-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007384304016"},{"key":"bibr3-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1177\/0960327110361501"},{"issue":"23","key":"bibr4-0960327111403172","first-page":"347","volume":"23","author":"Bavuno\u011flu I","year":"2004","journal-title":"Hum Exp Toxicol"},{"key":"bibr5-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-8-7"},{"key":"bibr6-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1081\/CLT-120016953"},{"key":"bibr7-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1097\/00063110-200306000-00006"},{"key":"bibr8-0960327111403172","doi-asserted-by":"publisher","DOI":"10.3923\/aje.2009.9.12"},{"key":"bibr9-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hci089"},{"key":"bibr10-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.2003.01910.x"},{"key":"bibr11-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1081\/CLT-120014644"},{"key":"bibr12-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1177\/0960327108099679"},{"key":"bibr13-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(96)70264-0"},{"issue":"4","key":"bibr14-0960327111403172","first-page":"1","volume":"4","author":"Jaba E","year":"2010","journal-title":"Rom Reg Sci Assoc"},{"key":"bibr15-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1191\/0960327106ht612oa"},{"key":"bibr16-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1177\/096032719401300711"},{"key":"bibr17-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1081\/CLT-50416"},{"key":"bibr18-0960327111403172","first-page":"88","volume":"3","author":"Sobhani AR","year":"2000","journal-title":"Arch Iran Med"},{"issue":"24","key":"bibr19-0960327111403172","first-page":"340","volume":"24","author":"Hirata Kiyotaka","year":"1998","journal-title":"Journal of the Nippon Hospital Pharmacists Association"},{"issue":"54","key":"bibr20-0960327111403172","first-page":"737","volume":"54","author":"Jaraczewska W","year":"1997","journal-title":"Przeglad Lekarski"},{"key":"bibr21-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1191\/096032799678839446"},{"key":"bibr22-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1191\/0960327104ht460oa"},{"issue":"39","key":"bibr23-0960327111403172","first-page":"371","volume":"39","author":"Hanssens Y","year":"2001","journal-title":"Clin Toxicol"},{"key":"bibr24-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1002\/jat.832"},{"key":"bibr25-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1191\/0960327105ht527oa"},{"key":"bibr26-0960327111403172","doi-asserted-by":"publisher","DOI":"10.4103\/0972-5229.58541"},{"key":"bibr27-0960327111403172","first-page":"489","volume":"34","author":"Chirasirisap K","year":"1992","journal-title":"Vet Hum Toxicol"},{"key":"bibr28-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1191\/0960327104ht487oa"},{"key":"bibr29-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1177\/096032719601500602"},{"key":"bibr30-0960327111403172","author":"Desalew M","year":"2010","journal-title":"Hum Exp Toxicol"},{"key":"bibr31-0960327111403172","volume-title":"Toxicologie Clinica de Urgenta","author":"Lionte C","year":"2005"},{"key":"bibr32-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1300\/J055V04N01_02"},{"issue":"8","key":"bibr33-0960327111403172","first-page":"119","volume":"8","author":"Lau FL","year":"1996","journal-title":"Emerg Med"},{"key":"bibr34-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/93.11.715"},{"key":"bibr35-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1177\/0960327107083017"},{"issue":"31","key":"bibr36-0960327111403172","first-page":"593","volume":"31","author":"Pinar A","year":"1993","journal-title":"Clin Toxicol"},{"key":"bibr37-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1177\/096032719801700604"},{"key":"bibr38-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1097\/00063110-200209000-00006"},{"key":"bibr39-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1136\/emj.15.4.257"},{"key":"bibr40-0960327111403172","doi-asserted-by":"publisher","DOI":"10.1177\/002580240204200310"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327111403172","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0960327111403172","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327111403172","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:46:23Z","timestamp":1777448783000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0960327111403172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,22]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1177\/0960327111403172"],"URL":"https:\/\/doi.org\/10.1177\/0960327111403172","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,22]]}}}