{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T06:10:25Z","timestamp":1793081425059,"version":"4.5.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T00:00:00Z","timestamp":1363737600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[2014,1]]},"abstract":"\n Context:<\/jats:title>\n Hair dyes are widely used and very popular xenobiotics. Most of these products contain paraphenylenediamine (PPD) that can cause methemoglobinemia. We here report a case of severe methemoglobinemia that we treated using large amounts of methylene blue.<\/jats:p>\n <\/jats:sec>\n \n Case details:<\/jats:title>\n A 30-year-old man visited a regional hospital with cyanosis. He was congenitally blind and had autism. For several weeks, he had mistaken hair dye for toothpaste. When he arrived at a regional hospital, he was drowsy with cyanosis and his initial serum methemoglobin (MetHb) level was 59.5%. After being treated with 2\u00a0mg\/kg methylene blue (1\u00a0mg\/kg\u00a0\u00d7\u00a02 administrations), he was transferred to a tertiary university hospital. Upon presentation at the Emergency Department in the tertiary hospital, his MetHb level was found to be 49.4% and his oxygen saturation was 80%. He was then admitted to the intensive care unit. After treatment with 4\u00a0mg\/kg methylene blue (1\u00a0mg\/kg\u00a0\u00d7\u00a04 administrations), he successfully recovered.<\/jats:p>\n <\/jats:sec>\n \n Discussion:<\/jats:title>\n Because PPD can result in serious methemoglobinemia, clinicians should test it in cyanotic patients who have been exposed to hair dye for an extended period.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0960327113480973","type":"journal-article","created":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T22:15:23Z","timestamp":1363817723000},"page":"103-105","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["A case of severe methemoglobinemia caused by hair dye poisoning"],"prefix":"10.1177","volume":"33","author":[{"given":"SM","family":"Ryoo","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CH","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BJ","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WY","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KS","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,3,20]]},"reference":[{"key":"bibr1-0960327113480973","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5359.50766"},{"key":"bibr2-0960327113480973","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.3297.421"},{"key":"bibr3-0960327113480973","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811421124"},{"key":"bibr4-0960327113480973","first-page":"871","volume":"55","author":"Bhargava P","year":"2007","journal-title":"J Assoc Physicians India"},{"key":"bibr5-0960327113480973","doi-asserted-by":"publisher","DOI":"10.1177\/0748233711399321"},{"key":"bibr6-0960327113480973","doi-asserted-by":"publisher","DOI":"10.1081\/JDI-100100857"},{"key":"bibr7-0960327113480973","doi-asserted-by":"publisher","DOI":"10.1258\/td.2010.090367"},{"key":"bibr8-0960327113480973","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(99)70167-8"},{"key":"bibr9-0960327113480973","doi-asserted-by":"publisher","DOI":"10.1097\/SMJ.0b013e318232139f"},{"key":"bibr10-0960327113480973","doi-asserted-by":"publisher","DOI":"10.1097\/00045391-200307000-00009"}],"container-title":["Human & Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327113480973","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0960327113480973","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327113480973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:53:44Z","timestamp":1777449224000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0960327113480973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,20]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1177\/0960327113480973"],"URL":"https:\/\/doi.org\/10.1177\/0960327113480973","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,20]]}}}