{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:35:12Z","timestamp":1777667712984,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T00:00:00Z","timestamp":1383177600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:p>The safety of dental amalgam as the primary material in dental restoration treatments has been debated since its introduction. It is widely accepted that amalgam restorations continuously release elemental mercury (Hg) vapor, which is inhaled and absorbed by the body and distributed to tissues, including the brain. The aim of the present study was to investigate whether the presence of amalgam fillings is correlated with brain Hg level. The Hg levels in the parietal lobes of the brains of 32 cadavers were analyzed with an atomic absorption spectrometer with the mercury hydride system. A total of 32 brain samples were tested; of these, 10 were from cadavers with amalgam fillings, while 22 of them were amalgam free. Hg was detected in 60.0% (6 of 10) of the samples in the amalgam group and in 36.3% (8 of 22) in the amalgam-free group. The average Hg level of the amalgam group was 0.97 \u00b1 0.83 \u00b5g\/g (minimum: 0.3 \u00b5g\/g and maximum: 2.34 \u00b5g\/g), and in the amalgam-free group, it was 1.06 \u00b1 0.57 \u00b5g\/g (minimum: 0.17 \u00b5g\/g and maximum: 1.76 \u00b5g\/g). The results of the present study showed no correlation between the presence of amalgam fillings and brain Hg level.<\/jats:p>","DOI":"10.1177\/0960327113509662","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T02:52:30Z","timestamp":1383274350000},"page":"873-877","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Human brain mercury levels related to exposure to amalgam fillings"],"prefix":"10.1177","volume":"33","author":[{"given":"E","family":"Erta\u015f","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Dentistry, Ondokuz Mayis University, Samsun, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ondokuz Mayis University, Samsun, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Turla","sequence":"additional","affiliation":[{"name":"Department of Forensic Science, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ES","family":"Karaarslan","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Dentistry, Gaziantep University, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Karaarslan","sequence":"additional","affiliation":[{"name":"Department of Forensic Science, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Yeditepe University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Eken","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Erciyes University, Kayseri, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,10,31]]},"reference":[{"key":"bibr1-0960327113509662","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8240.2004.tb00072.x"},{"key":"bibr2-0960327113509662","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-77782-3_4"},{"key":"bibr3-0960327113509662","doi-asserted-by":"publisher","DOI":"10.4103\/0972-0707.45247"},{"key":"bibr4-0960327113509662","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2007.04.004"},{"key":"bibr5-0960327113509662","doi-asserted-by":"publisher","DOI":"10.4103\/0971-6580.97191"},{"key":"bibr6-0960327113509662","unstructured":"McCabe FF, Walls AWG. 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