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In this study, the adult rats were exposed to DEHP and its effects on the uterus was evaluated. Healthy adult female rats were treated with DEHP orally (with dose level 0, 1, 10, and 100 mg\/kg body weight\/day) for 30 days. No significant changes in the body weight and wet uterine weight were observed. Ovarian hormones and their receptor levels in the uterus were increased. Histological studies exhibited the structural abnormalities such as decrease in diameter, thinning of the layers and disruption in the glandular epithelium.<\/jats:p>","DOI":"10.1177\/0960327116657601","type":"journal-article","created":{"date-parts":[[2016,7,29]],"date-time":"2016-07-29T21:29:43Z","timestamp":1469827783000},"page":"565-572","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":33,"title":["Impact of di-(2-ethylhexyl) phthalate on the uterus of adult Wistar rats"],"prefix":"10.1177","volume":"36","author":[{"given":"DB","family":"Somasundaram","sequence":"first","affiliation":[{"name":"Department of Endocrinology, University of Madras, Institute of Basic Medical Sciences."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Manokaran","sequence":"additional","affiliation":[{"name":"School of Allied Health Sciences, Manipal University, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BC","family":"Selvanesan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, University of Madras, Institute of Basic Medical Sciences."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RS","family":"Bhaskaran","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, University of Madras, Institute of Basic Medical Sciences."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,29]]},"reference":[{"key":"bibr1-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201000121"},{"key":"bibr2-0960327116657601","first-page":"293","volume":"65","author":"Albro PW","year":"1986","journal-title":"Environ Health Perspect"},{"key":"bibr3-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.5658"},{"key":"bibr4-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2008.12.015"},{"key":"bibr5-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1006\/taap.1994.1200"},{"key":"bibr6-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2010.09.015"},{"key":"bibr7-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2009.10.011"},{"key":"bibr8-0960327116657601","first-page":"1221","volume":"63","author":"Houston KD","year":"2003","journal-title":"Cancer Res"},{"key":"bibr9-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(87)90008-1"},{"key":"bibr10-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1096\/fj.07-9574LSF"},{"key":"bibr11-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.60478"},{"issue":"1","key":"bibr12-0960327116657601","doi-asserted-by":"crossref","first-page":"SP111","DOI":"10.2131\/jts.34.S111","volume":"34","author":"Takai R","year":"2009","journal-title":"J Toxicol Sci"},{"key":"bibr13-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-0436.1998.6240171.x"},{"key":"bibr14-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.11.5936"},{"key":"bibr15-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2004.04.015"},{"key":"bibr16-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.24.10661-10669.2004"},{"key":"bibr17-0960327116657601","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg254"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327116657601","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0960327116657601","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327116657601","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:49:04Z","timestamp":1777448944000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0960327116657601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,29]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["10.1177\/0960327116657601"],"URL":"https:\/\/doi.org\/10.1177\/0960327116657601","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,29]]}}}