{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:42:30Z","timestamp":1777668150364,"version":"3.51.4"},"reference-count":53,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T00:00:00Z","timestamp":1469491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Anthrax is a bacterial disease caused by the aerobic sporeforming bacterium Bacillus anthracis. It has been suggested that oxidative stress plays an important role in the pathogenesis of B. anthracis. The aim of this study was to investigate serum paraoxonase 1 (PON1) activity, catalase activity, malondialdehyde (MDA) levels, and superoxide dismutase (SOD) levels in patients with cutaneous anthrax.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods:<\/jats:title>\n                    <jats:p>Fifteen patients with cutaneous anthrax and 15 healthy controls were enrolled in this study. The serum MDA levels, SOD levels, paraoxonase, arylesterase, and catalase activities were measured using a spectrophotometer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The serum SOD levels, paraoxonase, arylesterase, and catalase activities were significantly lower in patients with cutaneous anthrax than in controls (for all, p &lt; 0.001), whereas MDA levels were significantly higher ( p &lt; 0.001). No significant correlation was found between serum paraoxonase activity, arylesterase activity, SOD levels, and MDA levels (all, p &gt; 0.05) in patients with cutaneous anthrax.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The current study was the first to show decreased antioxidant levels and increased oxidant levels in patients with cutaneous anthrax. Therefore, decreased PON1 activity may play a role in the pathogenesis of cutaneous anthrax.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0960327116661020","type":"journal-article","created":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T20:43:40Z","timestamp":1469565820000},"page":"663-669","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Serum paraoxonase activity and oxidative stress levels in patients with cutaneous anthrax"],"prefix":"10.1177","volume":"36","author":[{"given":"S","family":"Karadas","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Faculty of Medical, Yuzuncu Y\u0131l University, Van, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Aslan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medical, Yuzuncu Y\u0131l University, Van, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MR","family":"Ceylan","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease and Clinical Microbiology, Faculty of Medical, Yuzuncu Y\u0131l University, Van, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Sunnetcioglu","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease and Clinical Microbiology, Faculty of Medical, Yuzuncu Y\u0131l University, Van, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Bozan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medical, Yuzuncu Y\u0131l University, Van, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Kara","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Faculty of Medical, Yuzuncu Y\u0131l University, Van, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science and Art, Yuzuncu Y\u0131l University, Van, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,26]]},"reference":[{"key":"bibr1-0960327116661020","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1209.09070"},{"key":"bibr2-0960327116661020","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-4-200602210-00009"},{"key":"bibr3-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.091208.073255"},{"key":"bibr4-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.1999.00867.x"},{"key":"bibr5-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0691.2002.00500.x"},{"key":"bibr6-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.17.2236"},{"key":"bibr7-0960327116661020","first-page":"677","volume":"50","author":"Centers for Disease Control and Prevention","year":"2001","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"bibr8-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63548-1"},{"key":"bibr9-0960327116661020","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.2.893"},{"key":"bibr10-0960327116661020","first-page":"34","volume-title":"Principles and practice of infectious diseases","author":"Dieffenbach CW","year":"2005","edition":"6"},{"key":"bibr11-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1007\/BF03403527"},{"key":"bibr12-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/S1369-5274(99)80033-2"},{"key":"bibr13-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0013335"},{"key":"bibr14-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6603(08)60843-0"},{"key":"bibr15-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1993.tb17620.x"},{"key":"bibr16-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2004.09.035"},{"key":"bibr17-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(98)00095-1"},{"key":"bibr18-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2009.01.008"},{"key":"bibr19-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2009.02.026"},{"key":"bibr20-0960327116661020","doi-asserted-by":"publisher","DOI":"10.2143\/AC.59.6.2005242"},{"key":"bibr21-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1097\/01.mol.0000137227.54278.29"},{"key":"bibr22-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M200432-JLR200"},{"key":"bibr23-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.043398"},{"key":"bibr24-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.1224"},{"key":"bibr25-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.P900063-JLR200"},{"key":"bibr26-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2006.10.024"},{"key":"bibr27-0960327116661020","first-page":"889","volume":"50","author":"Centers for Disease Control and Prevention","year":"2001","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"bibr28-0960327116661020","first-page":"1126","volume":"35","author":"Eckerson HW","year":"1983","journal-title":"Am J Hum Genet"},{"key":"bibr29-0960327116661020","first-page":"391","volume":"30","author":"Haagen L","year":"1992","journal-title":"Eur J Clin Chem Clim Biochem"},{"key":"bibr30-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/34.3.497"},{"key":"bibr31-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-091302-2.50032-3"},{"key":"bibr32-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(79)90708-7"},{"key":"bibr33-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2006.07.005"},{"key":"bibr34-0960327116661020","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1209.09070"},{"key":"bibr35-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00515-08"},{"key":"bibr36-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1759(99)00146-5"},{"key":"bibr37-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V92.9.3007"},{"key":"bibr38-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.9.4068-4072.1998"},{"key":"bibr39-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1080\/10715760500164045"},{"key":"bibr40-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/43.7.1209"},{"key":"bibr41-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1002\/biof.5520340208"},{"key":"bibr42-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2006.03.023"},{"key":"bibr43-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2003.10.014"},{"key":"bibr44-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)63504-5"},{"key":"bibr45-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.75.6.573"},{"key":"bibr46-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000059724.08290.51"},{"key":"bibr47-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-2977(01)00144-9"},{"key":"bibr48-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.18.2283"},{"key":"bibr49-0960327116661020","first-page":"119","volume":"379","author":"La Du BN","year":"1999","journal-title":"Chem Biol Interact"},{"key":"bibr50-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2008.06.009"},{"key":"bibr51-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(98)00272-X"},{"key":"bibr52-0960327116661020","first-page":"813","volume":"17","author":"Dirican M","year":"2004","journal-title":"J Nephrol"},{"key":"bibr53-0960327116661020","doi-asserted-by":"publisher","DOI":"10.1161\/hq0901.094247"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327116661020","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0960327116661020","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0960327116661020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:49:07Z","timestamp":1777448947000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0960327116661020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,26]]},"references-count":53,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1177\/0960327116661020"],"URL":"https:\/\/doi.org\/10.1177\/0960327116661020","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,26]]}}}