{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:59:40Z","timestamp":1792166380057,"version":"4.4.0"},"reference-count":38,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Methanol toxicity is a significant health concern with potentially severe outcomes. This study aimed to investigate the prognostic factors of patients with methanol toxicity referred to Tabriz Sina Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A descriptive-analytical retrospective study was conducted in methanol toxicity patients admitted in Tabriz Sina Hospital since 2019 to 2021. Demographic characteristics and management methods were extracted from the patients\u2019 medical records.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients were predominantly male (91.3%) with a median age of 30\u201340\u00a0years. Winter accounted for 48.7% of cases. Coma (OR = 8.0, 95% CI: 3.2\u201319.9) and arrhythmia (OR = 5.5, 2.0\u201315.1) at admission, pH &lt;7.1 (OR = 4.2, 2.0\u20138.9), elevated creatinine (OR = 1.3\/mg\/dL, 1.1\u20131.6), opiate co-use (OR = 2.8, 1.2\u20136.5), and delayed ethanol therapy (&gt;3\u00a0h, OR = 2.3, 1.1\u20134.8) independently increased mortality risk. Bicarbonate, Eprex, and methylprednisolone reduced complications. Time from ingestion to admission (48\u201372\u00a0h) did not affect mortality, but delayed hemodialysis initiation worsened outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Early presentation and providing early therapeutic modalities have a significant impact on the mortality rate and the patients\u2019 outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09603271251358632","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T07:13:59Z","timestamp":1752822839000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical and laboratory prognostic factors associated with methanol toxicity outcomes in patients at Tabriz Sina Hospital: A retrospective study"],"prefix":"10.1177","volume":"44","author":[{"given":"Sajjad","family":"Ahmadi","sequence":"first","affiliation":[{"name":"Tabriz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9868-0080","authenticated-orcid":false,"given":"Ali","family":"Ostadi","sequence":"additional","affiliation":[{"name":"Tabriz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadi","family":"Chitsazi","sequence":"additional","affiliation":[{"name":"Tabriz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2224-4319","authenticated-orcid":false,"given":"Hossein","family":"Alikhah","sequence":"additional","affiliation":[{"name":"Maragheh University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,18]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.37471"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/03000605221081427"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2021.102445"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2021.11.026"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.15766\/mep_2374-8265.10740"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-018-1799-9"},{"issue":"1","key":"e_1_3_5_8_2","first-page":"27","article-title":"Epidemiology of alcohol poisoning and its outcome in the north-west of Iran","volume":"3","author":"Morteza Bagi HR","year":"2015","unstructured":"Morteza Bagi HR, Tagizadieh M, Moharamzadeh P, et al. 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