{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:18:13Z","timestamp":1792192693351,"version":"4.4.0"},"reference-count":4,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1983,4,1]],"date-time":"1983-04-01T00:00:00Z","timestamp":418003200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Toxicology"],"published-print":{"date-parts":[[1983,4]]},"abstract":"<jats:p>1 The authors performed haemodynamic studies in 8 cases of colchicine poisoning. The doses absorbed ranged between 9 and 160 mg (mean dose 39 mg). The haemodynamic study was performed between the 6th and 72nd h after intoxication, before and after plasma infusion (370 ml over a period of 20 minutes).<\/jats:p>\n                  <jats:p>2 Four patients had severe shock with decreased cardiac index (CI) and increased systemic vascular resistance (SVR). Four patients had a hyperkinetic state with increased CI and decreased SVR. The four patients with cardiac failure died, the others recovered.<\/jats:p>\n                  <jats:p>3 Haemodynamic study of acute colchicine poisoning is of therapeutic and prognostic interest. Hypovolaemia is always present. An initial decrease of cardiac performance is an index of severity with a lethal outcome.<\/jats:p>","DOI":"10.1177\/096032718300200201","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"169-173","source":"Crossref","is-referenced-by-count":38,"title":["Haemodynamic Studies in Eight Cases of Acute Colchicine Poisoning"],"prefix":"10.1177","volume":"2","author":[{"given":"Ph.","family":"Sauder","sequence":"first","affiliation":[{"name":"Service de Reanimation Medicale et Centre Anti-Poisons, C.H.U. B.P. No. 426, 67091 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Kopferschmitt","sequence":"additional","affiliation":[{"name":"Service de Reanimation Medicale et Centre Anti-Poisons, C.H.U. B.P. No. 426, 67091 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Jaeger","sequence":"additional","affiliation":[{"name":"Service de Reanimation Medicale et Centre Anti-Poisons, C.H.U. B.P. No. 426, 67091 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Mantz","sequence":"additional","affiliation":[{"name":"Service de Reanimation Medicale et Centre Anti-Poisons, C.H.U. B.P. No. 426, 67091 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1983,4,1]]},"reference":[{"key":"atypb1","volume-title":"Intoxication aigu\u00eb par la colchicine","author":"Bertrand, C.","year":"1979"},{"key":"atypb2","first-page":"1073","volume":"10","author":"Bismuth, C.","year":"1981","journal-title":"Nouv. Presse Med."},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1971.00480310100010"},{"key":"atypb4","volume-title":"Les insuffisances circulatoires mortelles des soixante douze premi\u00e8res heures au cours des intoxications massives par la colchicine. Importance du facteur cardiog\u00e9nique","author":"Surugue, R.","year":"1980"}],"container-title":["Human Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032718300200201","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032718300200201","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:47:21Z","timestamp":1777448841000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096032718300200201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,4]]},"references-count":4,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1983,4]]}},"alternative-id":["10.1177\/096032718300200201"],"URL":"https:\/\/doi.org\/10.1177\/096032718300200201","relation":{},"ISSN":["0144-5952"],"issn-type":[{"value":"0144-5952","type":"print"}],"subject":[],"published":{"date-parts":[[1983,4]]}}}