{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:33:39Z","timestamp":1777667619137,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1983,4,1]],"date-time":"1983-04-01T00:00:00Z","timestamp":418003200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Toxicology"],"published-print":{"date-parts":[[1983,4]]},"abstract":"<jats:p>1 The adsorptive capacities of two preparations of activated charcoal have been studied both in vitro and in vivo using aspirin as a test compound.<\/jats:p>\n                  <jats:p>2 The in vitro adsorptive capacities of the charcoal preparations were 477 mg of acetylsalicylic acid\/g effervescent charcoal ('Medicoal'); 359 mg\/g untreated standard charcoal ('Norit-A') and 482 mg\/g reheated charcoal ('Norit A').<\/jats:p>\n                  <jats:p>3 In vivo both charcoal preparations significantly reduced peak salicylate concentrations and salicylate availability, to a similar extent (analysis of variance P &lt; 0.001).<\/jats:p>\n                  <jats:p>4 Both charcoal preparations have similar capacities for adsorbing aspirin both in vitro and in vivo.<\/jats:p>","DOI":"10.1177\/096032718300200206","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"211-216","source":"Crossref","is-referenced-by-count":5,"title":["In Vitro and In Vivo Evaluation of Two Preparations of Activated Charcoal as Adsorbents of Aspirin"],"prefix":"10.1177","volume":"2","author":[{"given":"S.","family":"Dawling","sequence":"first","affiliation":[{"name":"Poisons Unit, Guy's Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Chand","sequence":"additional","affiliation":[{"name":"Poisons Unit, Guy's Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.A.","family":"Braithwaite","sequence":"additional","affiliation":[{"name":"Poisons Unit, Guy's Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Crome","sequence":"additional","affiliation":[{"name":"Poisons Unit, Guy's Hospital, London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1983,4,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1946.tb02599.x"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.3109\/15563657108990145"},{"key":"atypb3","first-page":"369","volume":"5","author":"Braithwaite, R.A.","year":"1978","journal-title":"Br. 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