{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:18:36Z","timestamp":1781104716228,"version":"3.54.1"},"reference-count":6,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1983,4,1]],"date-time":"1983-04-01T00:00:00Z","timestamp":418003200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Toxicology"],"published-print":{"date-parts":[[1983,4]]},"abstract":"<jats:p>1 Seventy five cases of ibuprofen overdose were recorded during a two year survey.<\/jats:p>\n                  <jats:p>2 Details of the symptoms, treatment and the eventual outcome are known for 64% of the cases. The majority of the patients had no symptoms or only mild symptoms such as nausea or vomiting.<\/jats:p>\n                  <jats:p>3 In the three cases where more serious symptoms were reported, the role of ibuprofen was not certain.<\/jats:p>\n                  <jats:p>4 Laboratory analyses available for 13 cases demonstrated that plasma ibuprofen concentrations of up to 704 mg\/l could be associated with no symptoms.<\/jats:p>\n                  <jats:p>5 The data suggest that ibuprofen is of low toxicity in acute overdose and that therapy used should be supportive only.<\/jats:p>","DOI":"10.1177\/096032718300200234","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"381-384","source":"Crossref","is-referenced-by-count":32,"title":["Acute Poisoning with Ibuprofen"],"prefix":"10.1177","volume":"2","author":[{"given":"H.","family":"Court","sequence":"first","affiliation":[{"name":"Poisons Unit, Guy's Hospital, London SE1 9RT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Streete","sequence":"additional","affiliation":[{"name":"Poisons Unit, Guy's Hospital, London SE1 9RT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.N.","family":"Volans","sequence":"additional","affiliation":[{"name":"Poisons Unit, Guy's Hospital, London SE1 9RT"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1983,4,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0307-742X(21)00075-8","volume":"5","author":"Adams, S.S.","year":"1979","journal-title":"Clinics in Rheumatic Diseases"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.282.6269.1073-a"},{"key":"atypb3","unstructured":"Department of Health and Social Security (Statistics and Research Division)."},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6194.819"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.281.6253.1458-a"},{"key":"atypb6","volume-title":"The Poisons Unit, Guy's Hospital","author":"Streete, P.J.","year":"1982"}],"container-title":["Human Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032718300200234","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032718300200234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:47:28Z","timestamp":1777448848000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096032718300200234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,4]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1983,4]]}},"alternative-id":["10.1177\/096032718300200234"],"URL":"https:\/\/doi.org\/10.1177\/096032718300200234","relation":{},"ISSN":["0144-5952"],"issn-type":[{"value":"0144-5952","type":"print"}],"subject":[],"published":{"date-parts":[[1983,4]]}}}