{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T14:03:57Z","timestamp":1777989837520,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1983,10,1]],"date-time":"1983-10-01T00:00:00Z","timestamp":433814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Toxicology"],"published-print":{"date-parts":[[1983,10]]},"abstract":"<jats:p>1 The 91 patients over the age of 10 (57 women and 32 men) with severe self-poisoning admitted to the ICU of a general hospital in Barcelona during the period 1974-1980 have been retrospectively studied.<\/jats:p>\n                  <jats:p>2 Previous suicidal attempts have been identified among 32 patients; 26 patients presented a history of personality disorders, and 19 had a neurological disease, a chronic physical illness, or a history of alcoholism.<\/jats:p>\n                  <jats:p>3 Sedative-hypnotic drugs were involved in about half the number of cases, and one fifth of total cases were due to tricyclic antidepressants and phenothiazines. Paracetamol was only involved in 2 cases, and heroin in another 2 cases.<\/jats:p>\n                  <jats:p>4 Many of the most severe morbidity manifestations were related to overdoses by intermediate-acting barbiturates. Two out of a total of 5 deaths were related to butalbitone overdose. Butalbitone had been ingested as a fixed-dose combination containing butalbitone, propyphenazone, and caffeine, which is freely dispensed as an analgesic in Spain.<\/jats:p>","DOI":"10.1177\/096032718300200407","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"625-632","source":"Crossref","is-referenced-by-count":6,"title":["Acute Severe Poisoning in Spain: Clinical Outcome Related to the Implicated Drugs"],"prefix":"10.1177","volume":"2","author":[{"given":"M.E.","family":"Frati","sequence":"first","affiliation":[{"name":"Division of Clinical Pharmacology, Autonomous University of Barcelona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Marruecos","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Hospital de Sant Pau, Barcelona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Porta","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacology, Autonomous University of Barcelona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.L.","family":"Mart\u00edn","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Faculty of Medicine, Autonomous University of Barcelona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.-R.","family":"Laporte","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacology, Autonomous University of Barcelona"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1983,10,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.3109\/15563658008989992"},{"key":"atypb2","first-page":"178","volume":"69","author":"Camp, J.","year":"1977","journal-title":"Med. Clin. Barcelona"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.3109\/15563658008990002"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1979.tb01648.x"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1977214497"},{"key":"atypb6","unstructured":"Harvey, S.C. (1980). Hypnotics and sedatives. In The pharmacological basis of therapeutics, eds L. S. Goodman, & A. Gilman, pp. 339-375. New York: Macmillan."},{"key":"atypb7","volume-title":"Clinical pharmacology of psychotherapeutic drugs","author":"Hollister, L.","year":"1978"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6069.1128"},{"key":"atypb9","volume-title":"Meeting of the WHO Drug Utilization Research Group","author":"Laporte, J.R."},{"key":"atypb10","unstructured":"Laporte, J.R., Capella, D., Gisbert, R., Porta, M., Frati, M.E., Garcia Santesmases, M.P., Garcia Inesta, A. (1981b). The utilization of sedative hypnotic drugs in Spain in Epidemiological impact ofpsychotropic drugs, eds. G. Tognoni, C. Bellantuono , & M. Lader, pp.137-149. Amsterdam : Elsevier\/North-Holland."},{"key":"atypb11","volume-title":"Patterns of use of psychotropic drugs in Spain in an international perspective","author":"Laporte, J.R."},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.64.6.616"},{"key":"atypb13","first-page":"879","volume":"225","author":"McCulloch, D.K.","year":"1981","journal-title":"Practitioner"},{"key":"atypb14","first-page":"27655","volume":"282","author":"Ministerio De Trabajo, Sanidad Y Seguridad Social.","year":"1981","journal-title":"Bolet\u00edn Oficial del Estado"},{"key":"atypb15","first-page":"893","volume":"10","author":"Ninet, J.","year":"1981","journal-title":"Nouv. Presse Med."},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1974.00320220105013"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.3109\/15563658108990020"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-7158.1979.tb13523.x"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.3109\/15563658108990330"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.282.6276.1613"}],"container-title":["Human Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032718300200407","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032718300200407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:47:35Z","timestamp":1777448855000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096032718300200407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,10]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1983,10]]}},"alternative-id":["10.1177\/096032718300200407"],"URL":"https:\/\/doi.org\/10.1177\/096032718300200407","relation":{},"ISSN":["0144-5952"],"issn-type":[{"value":"0144-5952","type":"print"}],"subject":[],"published":{"date-parts":[[1983,10]]}}}