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A simple kinetic model which satisfactorily describes methaemoglobin profiles after p-aminopropiophenone (PAPP) administration and 4-dimethylaminophenol (DMAP) administration has been developed. The two compounds differed nainly in their effective rates of elimination. The model less satisfactorily described methaemoglobin profiles after p-hydroxyaminopropiophenone (PHAPP) administration.<\/jats:p>","DOI":"10.1177\/096032718600500501","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"295-301","source":"Crossref","is-referenced-by-count":15,"title":["Kinetics of Methaemoglobin Production (1)"],"prefix":"10.1177","volume":"5","author":[{"given":"T.C.","family":"Marrs","sequence":"first","affiliation":[{"name":"Pathology and Clinical Toxicology Section, Chemical Defence Establishment, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.E.","family":"Bright","sequence":"additional","affiliation":[{"name":"Pathology and Clinical Toxicology Section, Chemical Defence Establishment, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1986,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01946202"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(72)90060-9"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4274(82)90141-2"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1007\/BF00569237"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4274(83)90087-5"},{"key":"atypb6","first-page":"1626","volume":"69","author":"Daunderer, M.","year":"1974","journal-title":"Med. 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