{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:57:04Z","timestamp":1777669024323,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1989,11,1]],"date-time":"1989-11-01T00:00:00Z","timestamp":625881600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Toxicology"],"published-print":{"date-parts":[[1989,11]]},"abstract":"<jats:p>1 In a prospective study of patients hospitalized for deliberate self-poisoning between 1978 and 1987 the number of admissions increased from 303 to 425. The annual incidence increased significantly for both women (P &lt; 0.05) and men (P &lt; 0.01). The mean age decreased significantly in the male group (P &lt; 0.05), but increased in the female group (P &lt; 0.05).<\/jats:p>\n                  <jats:p>2 The median latency time for patients presenting at the hospital was short; 3.7 h in 1978 and 2.9 h in 1987.<\/jats:p>\n                  <jats:p>3 There was a significant reduction in the percentage using barbiturates (9% in 1978 and 1% in 1987; P &lt; 0.001) and the use of benzodiazepines increased (18% in 1978 and 32% in 1987; P &lt; 0.05). The percentage of unconscious patients did not change significantly.<\/jats:p>\n                  <jats:p>4 In 1987 N-acetyl-cysteine was the most frequently used antidote. Physostigmine has almost been abandoned since 1978.<\/jats:p>\n                  <jats:p>5 Significantly more patients were hypotensive in 1978: 24% vs 11% in 1987; (P &lt; 0.001) and significantly less patients needed treatment in the central intensive care unit (2% in 1987 and 5% in 1978; P &lt; 0.05). Complications were few (8-10%) and the mortality low (approximately 1%) in both years studied.<\/jats:p>\n                  <jats:p>6 The mean duration of hospitalization in 1978 was 65 h vs 30 h in 1987, (P &lt; 0.001).<\/jats:p>","DOI":"10.1177\/096032718900800607","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"475-482","source":"Crossref","is-referenced-by-count":26,"title":["A Comparative Prospective Study of Self-poisoned Patients in Trondheim, Norway between 1978 and 1987: Epidemiology and Clinical Data"],"prefix":"10.1177","volume":"8","author":[{"given":"T.","family":"Rygnestad","sequence":"first","affiliation":[{"name":"Department of Medicine, Section of Nephrology and Department of Pharmacology and Toxicology, Faculty of Medicine, The University of Trondheim, Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1989,11,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5473.1265"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5474.1336"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1159\/000406245"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6105.90"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-73358-1_7"},{"key":"atypb6","volume-title":"Treatment of Common Acute Poisonings","author":"Matthew H.","year":"1975","edition":"3"},{"key":"atypb7","volume-title":"TDx\u00ae - system"},{"key":"atypb8","volume-title":"EMIT\u00ae Drug Assays"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/16.2.139"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1982.tb03160.x"},{"key":"atypb11","first-page":"562","volume":"19","author":"Good TJ","year":"1981","journal-title":"Science"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4347(84)80008-0"},{"key":"atypb13","volume-title":"97th and 107th issue","author":"Statistical Yearbook of Norway","year":"1978"},{"key":"atypb14","volume-title":"Population by age and marital status","year":"1984"},{"key":"atypb15","volume-title":"Statistical survey of Trondheim 1978","year":"1979"},{"key":"atypb16","volume-title":"Population Statistics. 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