{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:58:36Z","timestamp":1777669116561,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1990,5,1]],"date-time":"1990-05-01T00:00:00Z","timestamp":641520000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[1990,5]]},"abstract":"<jats:p>\n                    The purpose of this study was to evaluate the capacity of specific anti-digoxin Fab fragments to bind to and neutralize scilliroside and proscillaridin in acute poisoning. Apparent affinity constants were determined with values of 2.6 10\n                    <jats:sup>8<\/jats:sup>\n                    M\n                    <jats:sup>-1<\/jats:sup>\n                    for scilliroside and 3.8 10\n                    <jats:sup>7<\/jats:sup>\n                    M\n                    <jats:sup>-1<\/jats:sup>\n                    for proscillaridin. These results are in accordance with a possible in-vivo neutralization of these toxins.\n                  <\/jats:p>","DOI":"10.1177\/096032719000900313","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"191-193","source":"Crossref","is-referenced-by-count":16,"title":["Specific Anti-digoxin Fab Fragments: an Available Antidote for Proscillaridin and Scilliroside Poisoning?"],"prefix":"10.1177","volume":"9","author":[{"given":"A.","family":"Sabouraud","sequence":"first","affiliation":[{"name":"INSERM U26, Hopital Fernand Widal 200, Rue du Faubourg Saint-Denis 75475 Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Urtizberea","sequence":"additional","affiliation":[{"name":"INSERM U26, Hopital Fernand Widal 200, Rue du Faubourg Saint-Denis 75475 Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Cano","sequence":"additional","affiliation":[{"name":"INSERM U26, Hopital Fernand Widal 200, Rue du Faubourg Saint-Denis 75475 Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Garnier","sequence":"additional","affiliation":[{"name":"Centre Anti-poison, H\u00f4pital Fernand Widal 200, Rue du Faubourg Saint-Denis 75475 Paris Cedex 10, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Scherrmann","sequence":"additional","affiliation":[{"name":"INSERM U26, Hopital Fernand Widal 200, Rue du Faubourg Saint-Denis 75475 Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1990,5,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/hlca.19330160198","volume":"16","author":"Stoll A.","year":"1933","journal-title":"Helvetica Chimica Acta"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01468995"},{"key":"atypb3","first-page":"2355a","volume":"47","author":"Dybing F.","year":"1952","journal-title":"Acta Pharmacologica et Toxicologica"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(81)90182-9"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197604082941501"},{"key":"atypb6","first-page":"1","volume":"27","author":"Schemnann JM","year":"1989","journal-title":"Toxicology"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-2532(89)80037-7"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(80)90107-6"},{"key":"atypb9","author":"Chappey O.","year":"1989","journal-title":"Immunoanalyse et Biologie Sp\u00e9cialis\u00e9e"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(84)90403-X"},{"key":"atypb11","author":"Urtizberea M.","year":"1989","journal-title":"IABS Symposium Proceedings Utrecht"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032719000900313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032719000900313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:52:05Z","timestamp":1777449125000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096032719000900313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,5]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1990,5]]}},"alternative-id":["10.1177\/096032719000900313"],"URL":"https:\/\/doi.org\/10.1177\/096032719000900313","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,5]]}}}