{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:20:04Z","timestamp":1777666804113,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1994,5,1]],"date-time":"1994-05-01T00:00:00Z","timestamp":767750400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[1994,5]]},"abstract":"<jats:p>\n                    Intravenous pyridoxine was evaluated as an agent for the reversal of ethanol-induced central nervous depression in a randomised double blind controlled study of 108 patients presenting with a clinical diagnosis of acute ethanol intoxication to two accident and emergency departments. Level of consciousness, measured by a modified Glasgow coma scale, showed no significant change after a single 1 g dose of intravenous pyridoxine when compared to controls given saline, The mean fall in blood alcohol concentration after one hour was 33 mg dl\n                    <jats:sup>-1<\/jats:sup>\n                    (7.2 mmol l\n                    <jats:sup>-1<\/jats:sup>\n                    ) in both groups suggesting that pyridoxine has no antidotal action and no short term effect on the rate of metabolism of ethanol.\n                  <\/jats:p>","DOI":"10.1177\/096032719401300507","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"321-323","source":"Crossref","is-referenced-by-count":5,"title":["Intravenous Pyridoxine in Acute Ethanol Intoxication"],"prefix":"10.1177","volume":"13","author":[{"given":"S.","family":"Mardel","sequence":"first","affiliation":[{"name":"Accident and Emergency Department, Aberdeen Royal Infirmary, Aberdeen AB9 2ZB"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Phair","sequence":"additional","affiliation":[{"name":"Accident and Emergency Department, Leicester Royal Infirmary, Leicester LE1 5WW"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"O'Dwyer","sequence":"additional","affiliation":[{"name":"Accident and Emergency Department, Leicester Royal Infirmary, Leicester LE1 5WW"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.A.","family":"Henry","sequence":"additional","affiliation":[{"name":"Poisons Unit, Guy's Hospital, London, SE1 9RT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1994,5,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)92533-0"},{"key":"atypb2","unstructured":"Goldfrank LR          & Starke CL Toxicologic emergencies. 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