{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:23:11Z","timestamp":1777666991757,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1996,3,1]],"date-time":"1996-03-01T00:00:00Z","timestamp":825638400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[1996,3]]},"abstract":"<jats:p>A 58-year-old man fell into a trichloroethylene reservoir bath head first, during a maintenance degreasing bath and accidentally ingested the solvent. Although he showed deep coma, chemical burns and pneumonia on admission, these symptoms gradually subsided.<\/jats:p>\n                  <jats:p>The concentrations of trichloroethylene (TRI) and its metabolites, trichloroethanol (TCE) and trichloroacetic acid (TCA) in blood and urine were measured during hospitalization.<\/jats:p>\n                  <jats:p>Eight hours after the accident, the concentrations ofTRI and its metabolites in serum were 31.4 \u03bc g\/ml TRI, 16.5 \u03bcg\/ ml TCE and 79.5 \u03bcg\/ml TCA. The serum TRI concentration decreased to 4.3 \u03bcg\/ml on the following day. Elimination of TCE and TCA from serum occurred biphasically, the estimated half-lives of each metabolites being about 52.6 and 50.4 h in an initial fast phase and 268.3 and 277.2 h in a subsequent slow phase, respectively.<\/jats:p>\n                  <jats:p>\n                    Urinary TRI excretion persisted for the first 2 days. The urinary TCE and TCA excretions were longer than that of TRI with a biphasic decrease and the total amount of TCE excreted during the first 2 days was about two times that of TCA. The half-life of urinary TCE excretion (t\n                    <jats:sub>\u00bd<\/jats:sub>\n                    25.7 h) was shorter than that of TCA (t\n                    <jats:sub>\u00bd<\/jats:sub>\n                    52.1 h) in the fast phase but did no difference during the slow phase, with each half-time being about 166.3 h.\n                  <\/jats:p>\n                  <jats:p>The kinetics of TRI metabolites in blood and urine in this case were in slight agreement with the results following inhalation exposure previously reported in the literature.<\/jats:p>","DOI":"10.1177\/096032719601500312","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"254-258","source":"Crossref","is-referenced-by-count":12,"title":["Concentrations of trichloroethylene and its metabolites in blood and urine after acute poisoning by ingestion"],"prefix":"10.1177","volume":"15","author":[{"given":"M.","family":"Yoshida","sequence":"first","affiliation":[{"name":"Department of Public Health, St. Marianna University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Fukabori","sequence":"additional","affiliation":[{"name":"; Division of Work Environment and Occupational Health, The Institute for Science of Labour"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Hara","sequence":"additional","affiliation":[{"name":"; Division of Work Environment and Occupational Health, The Institute for Science of Labour"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Yuasa","sequence":"additional","affiliation":[{"name":"Department of Acute Medicine, St. Marianna University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Nakaaki","sequence":"additional","affiliation":[{"name":"Department of Environmental Hygiene, College of Environmental Health, Azabu University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Yamamura","sequence":"additional","affiliation":[{"name":"Department of Public Health, St. Marianna University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Public Health, St. Marianna University School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,3,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1080\/15287397709529469","volume":"2","author":"Waters EW","year":"1977","journal-title":"J Toxicol Environ Health"},{"key":"atypb2","volume-title":"Trichloroethylene, Environmental Criteria 50","author":"World Health Organization","year":"1985"},{"key":"atypb3","first-page":"311","volume":"21","author":"Nomiyama K.","year":"1979","journal-title":"Jap J Ind Health"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1007\/BF00378619"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1007\/BF00330110"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1007\/BF00377782"},{"key":"atypb7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF00539728","volume":"28","author":"Nomiyama K.","year":"1971","journal-title":"Int Arch Arbeitsmed"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1007\/BF01848261"},{"key":"atypb9","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/BF00570271","volume":"35","author":"Sorgo G.","year":"1976","journal-title":"Arch Toxicol"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1080\/00028896409342621"},{"key":"atypb11","first-page":"43","volume":"35","author":"Sato A.","year":"1978","journal-title":"Brit J Industr Med"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1007\/BF01709883"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1007\/BF00254128"},{"key":"atypb14","first-page":"60","volume":"17","author":"Soucek B.","year":"1960","journal-title":"Brit J Industr Med"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032719601500312","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032719601500312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:45:05Z","timestamp":1777448705000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096032719601500312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,3]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,3]]}},"alternative-id":["10.1177\/096032719601500312"],"URL":"https:\/\/doi.org\/10.1177\/096032719601500312","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,3]]}}}