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Ingestion of methyl salicylate poses the threat of severe, rapid-onset salicylate poisoning because of its liquid, concentrated form and lipid solubility. Excessive usage of these preparations in patients receiving warfarin may result in adverse interactions and bleedings. Methyl salicylate in topical analgesic preparations may cause irritant or allergic contact dermatitis and anaphylactic reactions. Physicians should fully appreciate the potential dangers from topical preparations containing methyl salicylate.<\/jats:p>","DOI":"10.1177\/096032719601500905","type":"journal-article","created":{"date-parts":[[2008,12,24]],"date-time":"2008-12-24T01:08:04Z","timestamp":1230080884000},"page":"747-750","source":"Crossref","is-referenced-by-count":57,"title":["Review : Potential dangers from topical preparations containing methyl salicylate"],"prefix":"10.1177","volume":"15","author":[{"given":"Thomas YK","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1996,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1097\/00006565-199310000-00008"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1177\/106002809502901214"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1990.tb01547.x"},{"key":"atypb4","first-page":"317","volume":"26","author":"Johnson PN","year":"1984","journal-title":"Vet Hum Toxicol"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193706000-00006"},{"key":"atypb6","first-page":"680","volume":"29","author":"Cauthen WL","year":"1989","journal-title":"J Fam Pract"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199207040-00005"},{"key":"atypb8","first-page":"699","volume":"268","author":"Chapman BJ","year":"1989","journal-title":"Q J Med"},{"key":"atypb9","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0022-3565(25)26029-3","volume":"132","author":"Davison C.","year":"1961","journal-title":"J Pharmacol Exp Ther"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1177\/106002809502901224"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1177\/096032719501400508"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1995.tb00583.x"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.72.844.109"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.3109\/15563659309000409"},{"key":"atypb15","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1542\/peds.62.3.404","volume":"62","year":"1978","journal-title":"Pediatrics"},{"key":"atypb16","volume-title":"Medical Toxicology: Diagnosis and Treatment of Human Poisoning","author":"Ellenhorn MJ","year":"1988"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1007\/BF00870985"},{"key":"atypb18","first-page":"442","volume":"39","author":"Heng Mcy.","year":"1987","journal-title":"Cutis"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6164.661"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1248\/bpb1978.14.663"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1979.tb02650.x"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1136\/adc.65.3.335"},{"key":"atypb23","first-page":"307","volume":"50","author":"Pec J.","year":"1992","journal-title":"Cutis"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1964.01600060080013"},{"key":"atypb25","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0022-3565(25)25723-8","volume":"128","author":"Quick AJ","year":"1960","journal-title":"J Pharmacol Exp Ther"},{"key":"atypb26","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-7158.1981.tb13695.x"},{"key":"atypb27","first-page":"455","volume":"2","author":"Tonkin AL","year":"1988","journal-title":"Clin Rheumatol"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.1136\/ard.43.3.411"},{"key":"atypb29","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.66.775.367"},{"key":"atypb30","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03440210038022"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1995.tb01540.x"},{"key":"atypb32","doi-asserted-by":"publisher","DOI":"10.1007\/BF03190157"},{"key":"atypb33","first-page":"36","volume":"43","author":"Speer F.","year":"1979","journal-title":"Ann Allergy"},{"key":"atypb34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1977.tb03708.x"}],"container-title":["Human &amp; 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