{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T04:19:17Z","timestamp":1782015557675,"version":"3.54.5"},"reference-count":23,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1998,6,1]],"date-time":"1998-06-01T00:00:00Z","timestamp":896659200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum Exp Toxicol"],"published-print":{"date-parts":[[1998,6]]},"abstract":"<jats:p>1 The influence of three oximes (obidoxime, HI-6 and the new asymmetric bispyridinium oxime BI-6) in combination with atropine on soman-induced cholinergic and stressogenic effects in rats was studied.<\/jats:p>\n                  <jats:p>2 The oxime BI-6 produced significantly higher reactivation of soman-inhibited blood and diaphragm cholinesterases than obidoxime. On the other hand, its reactivating effect was not so high as the effect of the oxime HI-6.<\/jats:p>\n                  <jats:p>3 There were not significant differences in the reactivation of soman-inhibited brain acetycholinesterase among all three oximes tested.<\/jats:p>\n                  <jats:p>4 The influence of the oxime BI-6 on soman-induced stressogenic effects was greater than the antistressogenic effects of HI-6 or obidoxime at 1 h or 3 h following soman poisoning.<\/jats:p>\n                  <jats:p>5 These findings confirm that the oxime BI-6 has no definite advantages over HI-6 in the antidotal treatment of soman poisoning but BI-6 is significantly more effective in rats than obidoxime, one of the oximes presently in use.<\/jats:p>","DOI":"10.1177\/096032719801700608","type":"journal-article","created":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T15:54:05Z","timestamp":1484495645000},"page":"331-335","source":"Crossref","is-referenced-by-count":4,"title":["A comparison of the efficacy of new asymmetric bispyridinium oxime BI-6 with                 other oximes (obidoxime, HI-6) against soman in rats"],"prefix":"10.1177","volume":"17","author":[{"given":"J","family":"Kassa","sequence":"first","affiliation":[{"name":"Purkyne Military Medical Academy, Hradec Kr\u00e1lov\u00e9,                         Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1998,6,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-7258(93)90066-M"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1002\/jat.2550140502"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4274(94)90121-X"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(65)90082-1"},{"key":"atypb5","first-page":"101","volume":"39","author":"Bajgar J.","year":"1996","journal-title":"Acta Medica (Hradec Kr\u00e1lov\u00e9)"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1007\/BF00292616"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1139\/y89-188"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(95)03091-S"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4274(91)90128-S"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1135\/cccc19980199"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1080\/09291018009359712"},{"key":"atypb12","volume-title":"Stress","author":"Schreiber V.","year":"1985"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(61)90145-9"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.15.4.374"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(66)90220-X"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-0590(81)80058-9"},{"key":"atypb17","first-page":"151","volume":"30","author":"Maksimovic M","year":"1980","journal-title":"Acta Pharmacologica Jugoslavica"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1007\/s002040050244"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1983.tb13573.x"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(92)90285-Z"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1016\/0197-0186(94)00151-J"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1016\/1056-8719(96)00027-5"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1007\/s002040050340"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032719801700608","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032719801700608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:46:19Z","timestamp":1777448779000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096032719801700608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,6]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1998,6]]}},"alternative-id":["10.1177\/096032719801700608"],"URL":"https:\/\/doi.org\/10.1177\/096032719801700608","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,6]]}}}