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Lead is capable of inhibiting calcium uptake in a non-competitive manner. As it has been described in other systems, lead is also capable of inhibiting calcium efflux by inhibiting Ca(Mg)-ATPase. Under physiological conditions, the function of ATPase reduces the effect of lead on calcium influx. However, in chronic intoxication a small increment of intracellular calcium is observed, indicating that lead is affecting calcium efflux mainly. We discuss the effects of lead on calcium equilibrium in erythrocytes.<\/jats:p>","DOI":"10.1177\/096032719901800303","type":"journal-article","created":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T17:47:53Z","timestamp":1484588873000},"page":"146-153","source":"Crossref","is-referenced-by-count":7,"title":["Effect of lead on the calcium transport in human erythrocyte"],"prefix":"10.1177","volume":"18","author":[{"given":"J V","family":"Calder\u00f3n-Salinas","sequence":"first","affiliation":[{"name":"Department of Biochemistry, CINVESTAV-IPN, M\u00e9xico City, M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M A","family":"Quintanar-Escorza","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, CINVESTAV-IPN, M\u00e9xico City, M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C E","family":"Hern\u00e1ndez-Luna","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Biological Sciences, UANL, San                         Nicol\u00e1s de los Garza, NL, M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M T","family":"Gonz\u00e1lez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Medicine, UNAM, M\u00e9xico                         City, M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1999,3,1]]},"reference":[{"key":"atypb1","first-page":"1","volume":"117","author":"Albert LM","year":"1991","journal-title":"Reviews Environmental Contamination Toxicology"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1177\/096032719601500406"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1177\/096032719601500502"},{"key":"atypb4","first-page":"45","volume":"14","author":"Goering P.","year":"1993","journal-title":"Neurotoxicology"},{"key":"atypb5","first-page":"77","volume":"14","author":"Simons TJB.","year":"1993","journal-title":"Neurotoxicology"},{"key":"atypb6","first-page":"153","volume":"3","author":"Calder\u00f3n SV","year":"1993","journal-title":"Journal Exposure Analysis and Environmental Epidemiology"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1177\/096032719601501102"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.94102s3153"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1007\/BF00228283"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(84)81135-7"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(89)90079-5"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1988.sp017323"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(92)90003-5"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(94)00311-C"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(87)90109-6"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)33892-4"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1986.sp016220"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1007\/BF01871648"}],"container-title":["Human &amp; Experimental Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032719901800303","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096032719901800303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:46:40Z","timestamp":1777448800000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096032719901800303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,3]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,3]]}},"alternative-id":["10.1177\/096032719901800303"],"URL":"https:\/\/doi.org\/10.1177\/096032719901800303","relation":{},"ISSN":["0960-3271","1477-0903"],"issn-type":[{"value":"0960-3271","type":"print"},{"value":"1477-0903","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,3]]}}}