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These behaviors have been shown to influence individuals\u2019 health perceptions and practices. Therefore, understanding the determinants of the Chinese public\u2019s cancer-related health information-seeking and -scanning behaviors on WeChat, as well as their behavioral outcomes, is essential. In response, this study applies the Comprehensive Model of Information Seeking (CMIS) to examine the antecedents, interrelationships, and behavioral outcomes of cancer information-seeking and scanning behaviors on WeChat. A cross-sectional online survey of 1478 WeChat users aged 18\u201369 was conducted between December 20\u2009and\u200924, 2023. Structural equation modeling (SEM) analysis revealed that perceived susceptibility, perceived credibility, and perceived utility were positively associated with WeChat users\u2019 information-scanning and -seeking behaviors, whereas perceived severity had a negative effect. WeChat self-efficacy was not significantly associated with either behavior. Additionally, individuals who frequently scanned cancer information were more likely to engage in information-seeking behavior, and both behaviors were positively associated with cancer-preventive behaviors. This study extends the CMIS framework to a non-Western social media context by examining cancer information-scanning and -seeking behaviors on WeChat, thereby strengthening its applicability to digital health information behaviors. The findings provide practical implications for health practitioners and library and information science professionals in designing more effective cancer communication and information services tailored to WeChat\u2019s media ecosystem.<\/jats:p>","DOI":"10.1177\/09610006251363633","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T16:32:31Z","timestamp":1757608351000},"page":"1291-1307","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Bridging cancer information scanning, seeking, and cancer-preventive behaviors: Testing the extended comprehensive model of information seeking"],"prefix":"10.1177","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6009-6395","authenticated-orcid":false,"given":"QianYing","family":"Ma","sequence":"first","affiliation":[{"name":"Universiti Putra Malaysia, Malaysia"},{"name":"Guangzhou Nanfang College, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5360-2959","authenticated-orcid":false,"given":"Jen-Sern","family":"Tham","sequence":"additional","affiliation":[{"name":"Universiti Putra Malaysia, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosmiza","family":"Bidin","sequence":"additional","affiliation":[{"name":"Universiti Putra Malaysia, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharifah","family":"Sofiah Syed Zainudin","sequence":"additional","affiliation":[{"name":"Universiti Putra Malaysia, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,9,11]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2885.2004.tb00310.x"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.3564"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10410236.2025.2497927"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-295X.84.2.191"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/10810730.2018.1493058"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2958.2002.tb00809.x"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10040544"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/10810730.2015.1018633"},{"key":"e_1_3_5_10_1","first-page":"23","volume-title":"Health Behavior and Health Education: Theory, Research, and Practice","author":"Champion V","year":"2008","unstructured":"Champion V, Skinner C (2008) The health belief model. 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