{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:57:43Z","timestamp":1777928263890,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T00:00:00Z","timestamp":1253145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:p>This study was undertaken to investigate whether levels of anti- Saccharomyces cerevisiae mannan antibodies (ASCMAs), a serological marker for Crohn\u2019s disease, seronegative spondyloarthritis and Behcet\u2019s disease, also correlate with systemic lupus erythematosus (SLE) in humans. Serum samples from healthy volunteers ( n\u00a0=\u00a0152) and patients with SLE ( n\u00a0=\u00a040) were compared for ASCMA-IgA, -IgG and -IgM levels using enzyme linked immunosorbent assays. ASCMA-IgG, but not IgM and IgA, prevalence was significantly raised in active SLE patients (57.5%) compared with healthy controls (8.5%). ASCMA-IgG levels in SLE patients during remission were relatively lower, indicating a possible correlation with disease activity. These results differ from a previous study, which did not detect a difference between ASCMA levels in SLE patients and healthy control. It remains to be evaluated whether elevated ASCMA-levels are common to all rheumatic disorders.<\/jats:p>","DOI":"10.1177\/0961203309105131","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T06:08:29Z","timestamp":1253167709000},"page":"1087-1090","source":"Crossref","is-referenced-by-count":21,"title":["Elevated levels of serum antibodies against Saccharomyces cerevisiae mannan in patients with systemic lupus erythematosus"],"prefix":"10.1177","volume":"18","author":[{"given":"H","family":"Dai","sequence":"first","affiliation":[{"name":"Department of Immunology, Peking University Health Science Center, Peking University, Beijing, China; Key Laboratory for Immunology, Ministry for Public Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, People\u2019s Hospital, Peking University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Immunology, Peking University Health Science Center, Peking University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Immunology, Peking University Health Science Center, Peking University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XM","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Immunology, Peking University Health Science Center, Peking University, Beijing, China; Key Laboratory for Immunology, Ministry for Public Health, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,9,17]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1019926121972"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1191\/0961203306lu2331oa"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.04.030"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.060228"},{"key":"atypb5","first-page":"S21","volume":"20","author":"Krause I","year":"2002","journal-title":"Clin Exp Rheumatol"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.2003.02166.x"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.5.455"},{"key":"atypb8","first-page":"920","volume":"31","author":"Riente L","year":"2004","journal-title":"J Rheumatol"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780251101"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1177\/0961203308089989"},{"key":"atypb11","unstructured":"11 Veys EM\u2004 Mielants H\u2004. 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