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For example, anti-neutrophil cytoplasmic autoantibodies directed against perinuclear or cytoplasmic proteins of neutrophils are present in a high percentage of patients with systemic vasculitis, and they can be suggestive of Wegener\u2019s Granulomatosis and Microscopic Polyangiitis. This case report underlines the necessity of more specific laboratory and instrumental testing if clinical signs and\/or other parameters (p-ANCA and\/or c-ANCA staining and\/or urinalysis) are suggestive of systemic vasculitis.<\/jats:p>","DOI":"10.1177\/0961203309349740","type":"journal-article","created":{"date-parts":[[2010,2,4]],"date-time":"2010-02-04T20:41:20Z","timestamp":1265316080000},"page":"655-657","source":"Crossref","is-referenced-by-count":2,"title":["Late onset of pANCA renal and pulmonary vasculitis in a girl affected by undifferentiated connective tissue disease"],"prefix":"10.1177","volume":"19","author":[{"given":"MG","family":"Alpigiani","sequence":"first","affiliation":[{"name":"Department of Pediatrics, G Gaslini Institute, Genoa, Italy,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Calcagno","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, G Gaslini Institute, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Salvati","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, G Gaslini Institute, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GA","family":"Rossi","sequence":"additional","affiliation":[{"name":"Department of Pneumology, G Gaslini Institute, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Barbano","sequence":"additional","affiliation":[{"name":"Department of Nephrology, G Gaslini Institute, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Ghiggeri","sequence":"additional","affiliation":[{"name":"Department of Nephrology, G Gaslini Institute, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Lorini","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, G Gaslini Institute, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,2,4]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-005-1911-z"},{"key":"atypb2","first-page":"35","volume":"60","author":"Mosca M.","year":"2008","journal-title":"Reumatismo"},{"key":"atypb3","first-page":"313","volume":"21","author":"Bodolay E.","year":"2003","journal-title":"Clin Exp Rheumatol"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780330807"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780370206"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/41.10.1138"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.046300"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1136\/ard.58.10.644"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0961203309349740","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0961203309349740","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:08:59Z","timestamp":1777676939000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0961203309349740"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2,4]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["10.1177\/0961203309349740"],"URL":"https:\/\/doi.org\/10.1177\/0961203309349740","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2,4]]}}}