{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:59:09Z","timestamp":1777928349429,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T00:00:00Z","timestamp":1310947200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:p>\n                    Antiphospholipid syndrome (APS) is an autoimmune disease characterized by recurrent thrombotic events, miscarriages and thrombocytopenia with persistently positive antiphospholipid antibodies.\n                    <jats:sup>1 , 2<\/jats:sup>\n                    APS may be isolated (primary APS) or associated to a connective tissue disease, most often systemic lupus erythematosus (SLE).\n                    <jats:sup>1 , 2<\/jats:sup>\n                    APS usually affects young patients before the fifth decade\n                    <jats:sup>3<\/jats:sup>\n                    with stroke being the commonest neurological manifestation.\n                    <jats:sup>4<\/jats:sup>\n                    Various other neurological manifestations are being recognized in patients with APS including migraine, epilepsy, multi-infarct dementia and chorea.\n                    <jats:sup>2<\/jats:sup>\n                    The pathological process underlying the neurological manifestations remains obscure.\n                    <jats:sup>1 , 2<\/jats:sup>\n                    Herein we report a case of primary APSpresenting with a group of unusual neurological manifestations in a 68-year-old woman.\n                  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