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On the other hand, association between haematological malignities and SLE \u2013 in terms of pathophysiology and molecular genetics \u2013 is an obscure entity which has not been clarified evidently to date. Herein, we present a six-year-old female with the diagnosis of SLE who developed acute lymphoblastic leukaemia following a period of myelodysplasia. It could possibly be coincidental; however, persistent cytopenia, prominent dysplasia on bone marrow smears and azathioprine treatment may be considered as possible triggers for the development of leukaemia in the present case.<\/jats:p>","DOI":"10.1177\/0961203312436859","type":"journal-article","created":{"date-parts":[[2012,2,13]],"date-time":"2012-02-13T21:15:39Z","timestamp":1329167739000},"page":"910-913","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Acute lymphoblastic leukaemia in a child with systemic lupus erythematosus"],"prefix":"10.1177","volume":"21","author":[{"given":"M","family":"Gokce","sequence":"first","affiliation":[{"name":"Pediatric Haematology Division, Hacettepe Medical Faculty, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Bulus","sequence":"additional","affiliation":[{"name":"Pediatric Haematology Division, Hacettepe Medical Faculty, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Bilginer","sequence":"additional","affiliation":[{"name":"Pediatric Rheumatology Division, Hacettepe Medical Faculty, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Gumruk","sequence":"additional","affiliation":[{"name":"Pediatric Haematology Division, Hacettepe Medical Faculty, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Besbas","sequence":"additional","affiliation":[{"name":"Pediatric Rheumatology Division, Hacettepe Medical Faculty, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Cetin","sequence":"additional","affiliation":[{"name":"Pediatric Haematology Division, Hacettepe Medical Faculty, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,2,13]]},"reference":[{"key":"bibr1-0961203312436859","doi-asserted-by":"publisher","DOI":"10.1177\/0961203307087611"},{"key":"bibr2-0961203312436859","doi-asserted-by":"publisher","DOI":"10.1177\/0961203310374339"},{"key":"bibr3-0961203312436859","doi-asserted-by":"crossref","unstructured":"Hwang J, Kim HJ, Oh JM, et al. Outcome of reclassification of World Health Organization (WHO) class III under International Society of Nephrology\u2013Renal Pathology Society (ISN\u2013RPS) classification: Retrospective observational study.\n                      Rheumatol Int.\n                      Epub ahead of print 27 March 2011. 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