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It is therefore challenging to determine the treatment that is best suited for this subset of patients, especially if initial conventional therapy for GBS fails. We present two cases of GBS-like acute axonal neuropathies, one with acute motor axonal neuropathy (AMAN), and another with acute motor sensory axonal neuropathy (AMSAN), presenting early in the course of SLE. The first case failed to respond to therapy with intravenous immunoglobulins (IVIG) and plasmapheresis, but achieved a favorable outcome when high-dose glucocorticoids along with low-dose intravenous (IV) cyclophosphamide pulses were given. The second case responded favorably to high-dose glucocorticoids, IVIG, and low-dose IV cyclophosphamide pulses. Both patients have remained in clinical remission and without neurologic sequelae after 10 and three years of follow-up, respectively.<\/jats:p>","DOI":"10.1177\/0961203313476358","type":"journal-article","created":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T09:04:31Z","timestamp":1361783071000},"page":"324-327","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":26,"title":["Efficacy of low-dose intravenous cyclophosphamide in systemic lupus erythematosus presenting with Guillain-Barr\u00e9 syndrome-like acute axonal neuropathies: report of two cases"],"prefix":"10.1177","volume":"22","author":[{"given":"Y","family":"Santiago-Casas","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, Puerto Rico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RA","family":"Peredo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Rheumatology, University of Michigan Medical School, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LM","family":"Vil\u00e1","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, Puerto Rico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,2,25]]},"reference":[{"key":"bibr1-0961203313476358","first-page":"1061","volume":"21","author":"McNicholl JM","year":"1994","journal-title":"J Rheumatol"},{"key":"bibr2-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1097\/01.nrl.0000117821.35196.0b"},{"key":"bibr3-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/28.5.440"},{"key":"bibr4-0961203313476358","first-page":"314","volume":"30","author":"Robson MG","year":"1994","journal-title":"Br J Rheumatol"},{"key":"bibr5-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1097\/00124743-199912000-00010"},{"key":"bibr6-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.4.840"},{"key":"bibr7-0961203313476358","first-page":"300","volume":"159","author":"Ait Benhaddou E","year":"2003","journal-title":"Rev Neurol (Paris)"},{"key":"bibr8-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1986.00520060066020"},{"key":"bibr9-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.3.695"},{"key":"bibr10-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2008.08.033"},{"key":"bibr11-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67665-9"},{"key":"bibr12-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21830"},{"key":"bibr13-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1177\/0961203310392427"},{"key":"bibr14-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410390105"},{"key":"bibr15-0961203313476358","doi-asserted-by":"publisher","DOI":"10.1097\/00124743-200110000-00014"},{"key":"bibr16-0961203313476358","first-page":"876","volume":"44","author":"Levine SR","year":"1987","journal-title":"Lupus anticoagulants and anticardiolipin antibodies. 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