{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T13:54:42Z","timestamp":1778594082792,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2013,6,11]],"date-time":"2013-06-11T00:00:00Z","timestamp":1370908800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Subepidermal bullous lesions and toxic epidermal necrolysis-like (TEN-like) lesions can occur in patients with systemic lupus erythematosus (SLE). In this report, we describe a case of a patient previously diagnosed with SLE who experienced TEN-like skin lesions with unusual subacute progression in the context of the current literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We present a recent case of TEN-like lupus erythematosus and review of studies published in English identifying SLE cases mimicking TEN, accessed via PubMed and Google Scholar databases. The keywords used in the search were: TEN, SLE, TEN-like SLE, and TEN-like lesions. The search covered all articles from January 1980 to November 2011.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A 52-year-old male presented with fatigue, weakness, and weight loss (23\u2009kg in two months). Skin redness started across nose and cheeks six months before admission. Bilateral pleural effusions were observed in a thorax tomography taken in the referral hospital two months prior to admission. Because of articular involvement, antinuclear antibody (ANA), and anti-dsDNA positivity, the patient was diagnosed with SLE. We initiated a punch skin biopsy, and the findings were consistent with Stevens-Johnson syndrome. There was marked basal layer necrosis in the epidermis, and there was predominantly lymphohistiocytic infiltrate in the dermis. A total of 22 cases, including our case, with TEN-like lupus erythematosus were reported in the literature. In addition, cutaneous lupus had positive ANAs in 18 of 22 patients (81.8%). The patients were aged 12 to 76 years; 21 cases were women and only one patient was male.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Skin involvement, including the rare variant of TEN-like acute cutaneous SLE, is very common among SLE patients. The acute syndrome of pan-epidermolysis or apoptotic pan-epidermolysis may become a useful designation when considering a clinical diagnosis of drug-induced TEN or SLE. Further studies are required to verify our findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0961203313492242","type":"journal-article","created":{"date-parts":[[2013,6,11]],"date-time":"2013-06-11T20:16:13Z","timestamp":1370981773000},"page":"839-846","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":31,"title":["A case of toxic epidermal necrolysis-like skin lesions with systemic lupus erythematosus and review of the literature"],"prefix":"10.1177","volume":"22","author":[{"given":"G Yildirim","family":"Cetin","sequence":"first","affiliation":[{"name":"Sutcu Imam University, Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Kahramanmaras, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Sayar","sequence":"additional","affiliation":[{"name":"Sutcu Imam University, Medical Faculty, Department of Pathology, Kahramanmaras, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Ozkan","sequence":"additional","affiliation":[{"name":"Sutcu Imam University, Medical Faculty, Department of Radiology, Kahramanmaras, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Kurtulus","sequence":"additional","affiliation":[{"name":"Sutcu Imam University, Medical Faculty, Department of Internal medicine, Kahramanmaras, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Kesici","sequence":"additional","affiliation":[{"name":"Sutcu Imam University, Medical Faculty, Department of Internal medicine, Kahramanmaras, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Sayarl\u0131oglu","sequence":"additional","affiliation":[{"name":"Sutcu Imam University, Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Kahramanmaras, 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