{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:01:40Z","timestamp":1777928500447,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T00:00:00Z","timestamp":1410825600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p>Adherence to treatment is fundamental for its success. It comprises compliance combined with persistency and should be constantly reassessed. This is true in all medical situations. In antiphospholipid syndrome (or Hughes\u2019 syndrome), in addition to taking the medication at the planned time so that its effect on blood can be assessed and the dose adjusted if necessary, all patients must incorporate healthy habits with a treatment that is lifelong and will be influenced by dietary changes and the use of many other medications. Following a regime for the treatment to be effective, and to avoid serious complications, often creates the sensation of \u2018living on a tightrope\u2019 for both the patients and the health care providers. Patient education along with constant monitoring using proper communication settings and tools are certain to improve adherence and outcomes.<\/jats:p>","DOI":"10.1177\/0961203314536480","type":"journal-article","created":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T06:49:54Z","timestamp":1410850194000},"page":"1265-1268","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Patient\u2013health care provider relationship: how can it impact on APS (Hughes\u2019 syndrome) adherence to treatment?"],"prefix":"10.1177","volume":"23","author":[{"given":"RA","family":"Levy","sequence":"first","affiliation":[{"name":"Faculdade de Ci\u00eancias M\u00e9dicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil"},{"name":"Centro de Imunoterapia de Ipanema \u2013 CITIPA, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Signorelli","sequence":"additional","affiliation":[{"name":"Hospital Universit\u00e1rio Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"},{"name":"Hospital Universit\u00e1rio Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,9,16]]},"reference":[{"key":"bibr1-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp0904813"},{"key":"bibr2-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1002\/art.24368"},{"key":"bibr3-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(99)00057-4"},{"key":"bibr4-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1590\/S0482-50042013000200005"},{"key":"bibr5-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1177\/0961203314522341"},{"key":"bibr6-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2012.01.006"},{"key":"bibr7-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathophys.2010.04.010"},{"key":"bibr8-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2009.05.001"},{"key":"bibr9-0961203314536480","first-page":"508","volume":"19","author":"Asherson RA","year":"1992","journal-title":"J Rheumatol"},{"key":"bibr10-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-011-0218-2"},{"key":"bibr11-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.10.014"},{"key":"bibr12-0961203314536480","doi-asserted-by":"crossref","unstructured":"Klack K, de Carvalho JF. Vitamin K: Metabolism, sources and interaction with the anticoagulant warfarin.\n                      Rev Bras Reumatol\n                      2006; 46: 398\u2013406.","DOI":"10.1590\/S0482-50042006000600007"},{"key":"bibr13-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1343"},{"key":"bibr14-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8287.2011.02033.x"},{"key":"bibr15-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.08.054"},{"key":"bibr16-0961203314536480","unstructured":"Barbar\u00e1 F, Levy R, Signorelli F. Website to monitoring patients with antiphospholipid syndrome. Abstract 0277 presented at 14th International Congress on Antiphospholipid Antibodies and 4th Latin American Congress of Autoimmunity, Rio de Janeiro, 2013."},{"key":"bibr17-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-011-0555-z"},{"key":"bibr18-0961203314536480","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.01.053"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0961203314536480","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0961203314536480","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0961203314536480","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:14:42Z","timestamp":1777677282000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0961203314536480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,16]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1177\/0961203314536480"],"URL":"https:\/\/doi.org\/10.1177\/0961203314536480","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,16]]}}}