{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:07:18Z","timestamp":1788826038755,"version":"build-2803163510"},"reference-count":25,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2015,7,10]],"date-time":"2015-07-10T00:00:00Z","timestamp":1436486400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Pericardial involvement is a frequent manifestation of systemic lupus erythematosus (SLE). Growing evidence suggests that colchicine may be useful for acute or recurrent pericarditis. We report for the first time a series of 10 consecutive cases of SLE with pericarditis treated with colchicine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Inclusion criteria in this retrospective study were diagnosis of SLE, pericarditis and receiving colchicine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 10 consecutive cases of SLE with pericarditis treated with colchicine (nine women, mean age at the index pericarditis 35\u2009\u00b1\u200912 years). Pericarditis was the initial manifestation of SLE for two patients, whereas eight patients had SLE lasting for a median of 2.5 years (15 days to 13 years) and had received prednisone ( n\u2009=\u20097, 2\u201330\u2009mg\/d), hydroxychloroquine ( n\u2009=\u20097), azathioprine ( n\u2009=\u20093), methotrexate ( n\u2009=\u20092), and mycophenolate mofetil ( n\u2009=\u20091). For six patients, pericarditis was associated with other SLE manifestations. Altogether, colchicine avoided the use ( n\u2009=\u20092) or increase in dosage ( n\u2009=\u20095) of steroids in seven cases; the increase in steroids dosage was minimal for two patients. Colchicine 1\u2009mg was given for a median of 39 days (10 days to 54 months). Symptoms completely resolved after a median of 2.5 days (1\u201330 days) after initiation of colchicine. Colchicine was maintained or resumed in six patients to prevent recurrence, with no further relapse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Colchicine may be safe and effective in treating SLE pericarditis and used as a steroids-sparing agent. These preliminary results need to be confirmed in a larger study with longer follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0961203315593169","type":"journal-article","created":{"date-parts":[[2015,7,11]],"date-time":"2015-07-11T19:58:52Z","timestamp":1436644732000},"page":"1479-1485","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":36,"title":["Colchicine: a simple and effective treatment for pericarditis in systemic lupus erythematosus? A report of 10 cases"],"prefix":"10.1177","volume":"24","author":[{"given":"N","family":"Morel","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris-Descartes, Paris, France; AP-HP, H\u00f4pital Cochin, Centre de r\u00e9f\u00e9rence maladies auto-immunes et syst\u00e9miques rares, Service de M\u00e9decine Interne, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Bonjour","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Descartes, Paris, France; AP-HP, H\u00f4pital Cochin, Centre de r\u00e9f\u00e9rence maladies auto-immunes et syst\u00e9miques rares, Service de M\u00e9decine Interne, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Le Guern","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Descartes, Paris, France; AP-HP, H\u00f4pital Cochin, Centre de r\u00e9f\u00e9rence maladies auto-immunes et syst\u00e9miques rares, Service de M\u00e9decine Interne, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Le Jeunne","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Descartes, Paris, France; AP-HP, H\u00f4pital Cochin, Centre de r\u00e9f\u00e9rence maladies auto-immunes et syst\u00e9miques rares, Service de M\u00e9decine Interne, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Mouthon","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Descartes, Paris, France; AP-HP, H\u00f4pital Cochin, Centre de r\u00e9f\u00e9rence maladies auto-immunes et syst\u00e9miques rares, Service de M\u00e9decine Interne, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J-C","family":"Piette","sequence":"additional","affiliation":[{"name":"Universit\u00e9 UPMC, Paris, France; AP-HP, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Centre de r\u00e9f\u00e9rence maladies auto-immunes et syst\u00e9miques rares, Service de M\u00e9decine Interne, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Costedoat-Chalumeau","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Descartes, Paris, France; AP-HP, H\u00f4pital Cochin, Centre de r\u00e9f\u00e9rence maladies auto-immunes et syst\u00e9miques rares, Service de M\u00e9decine Interne, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,7,10]]},"reference":[{"key":"bibr1-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1191\/0961203305lu2200oa"},{"key":"bibr2-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2011-300054"},{"key":"bibr3-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(90)90329-Y"},{"key":"bibr4-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1136\/ard.51.2.156"},{"key":"bibr5-0961203315593169","doi-asserted-by":"publisher","DOI":"10.4065\/74.3.275"},{"key":"bibr6-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.070367"},{"key":"bibr7-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.02.002"},{"key":"bibr8-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1191\/0961203305lu2187oa"},{"key":"bibr9-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1080\/AC.68.6.8000011"},{"key":"bibr10-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1002\/art.27601"},{"key":"bibr11-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-007834"},{"key":"bibr12-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2010.09.010"},{"key":"bibr13-0961203315593169","first-page":"781","volume":"370","author":"Imazio M","year":"2013","journal-title":"N Engl J Med"},{"key":"bibr14-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62709-9"},{"key":"bibr15-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"bibr16-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.82.4.1117"},{"key":"bibr17-0961203315593169","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-009-0241-6"},{"key":"bibr18-0961203315593169","unstructured":"Haute Autorit\u00e9 de Sant\u00e9 (HAS), http:\/\/www.has-sante.fr\/portail\/upload\/docs\/application\/pdf\/2010-03\/ald_21_pnds_lupus_web.pdf (2010, accessed 2014)."},{"key":"bibr19-0961203315593169","doi-asserted-by":"publisher","DOI":"10.1191\/096120301668183556"},{"key":"bibr20-0961203315593169","doi-asserted-by":"crossref","unstructured":"Bruce IN, O\u2019Keeffe AG, Farewell V\n                      ,\n                      et\u00a0al. Factors associated with damage accrual in patients with systemic lupus erythematosus: Results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort.\n                      Ann Rheum Dis.\n                      Epub ahead of print 16 May 2014. 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