{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:03:20Z","timestamp":1777928600738,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Progressive outer retinal necrosis syndrome (PORN) is a severe clinical variant of necrotizing herpetic chorioretinitis, which occurs almost exclusively in patients with advanced acquired immunodeficiency syndrome (AIDS). To date, only a few cases of PORN have been reported in patients, mostly among those who were immunocompromised. To our knowledge, only one case of PORN in a patient with systemic lupus erythematosus (SLE) has been described. We report the case of a 44-year old HIV-negative patient with lupus nephritis, whom was being treated by mycophenolate mophetil (MMF), arechin and prednisone. After 14 months of MMF therapy, the patient revealed PORN symptoms; and several months later, the patient developed Type B primary central nervous system lymphoma (PCNSL). PORN is usually compared to acute retinal necrosis (ARN) syndrome, because of having the same causative agent: varicella zoster virus (VZV). There are also some similarities in clinical findings. Our observation supports the hypothesis that PORN symptoms in HIV-negative patients can be an intermediate form between ARN and PORN, and can vary according to the patient\u2019s immune status.<\/jats:p>","DOI":"10.1177\/0961203316646464","type":"journal-article","created":{"date-parts":[[2016,5,14]],"date-time":"2016-05-14T00:15:08Z","timestamp":1463184908000},"page":"1610-1614","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Progressive outer retinal necrosis syndrome in the course of systemic lupus erythematosus"],"prefix":"10.1177","volume":"25","author":[{"given":"A","family":"Turno-Kr\u0119cicka","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Wroc\u0142aw Medical University, Wroclaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Tomczyk-Socha","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Wroc\u0142aw 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