{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:04:54Z","timestamp":1777928694721,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2018,1,4]],"date-time":"2018-01-04T00:00:00Z","timestamp":1515024000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To detect the frequency of psychological alterations in primary antiphospholipid syndrome patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty-six primary antiphospholipid syndrome patients were analyzed by a psychological interview using a standard protocol and review of medical charts. Clinical manifestations, associated comorbidities, antiphospholipid antibodies, and treatment were also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean age was 44.2\u2009\u00b1\u200910.8 years, 29 (80%) were women and 29 (80%) were of Caucasian race. The mean duration of disease was 7.3\u2009\u00b1\u20095.2 years. The frequency of the presence of psychological alterations was 97.1%. Family dependence was observed in 14 (40%), memory loss in 12 (34.3%), social losses in 12 (34.3%), sexual limitations in seven (20%), sadness in six (17.1%), severe speech limitation in four (11.4%), anxiety in three (8.6%), learning difficulty in two (5.7%), generalized phobia in two (5.7%), suicide ideation in one (2.6%), agoraphobia in one (2.6%), and obsessive-compulsive disorder in one (2.6%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrated that almost all primary antiphospholipid syndrome patients have psychological alterations. These data reinforce the need for psychological evaluation in primary antiphospholipid syndrome patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0961203317751063","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T00:23:27Z","timestamp":1515111807000},"page":"837-840","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Frequency of psychological alterations in primary antiphospholipid syndrome: preliminary study"],"prefix":"10.1177","volume":"27","author":[{"given":"M","family":"Sadetski","sequence":"first","affiliation":[{"name":"Psychological Division, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M L","family":"Tourinho Moretto","sequence":"additional","affiliation":[{"name":"Psychological Division, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R P","family":"Correia de Araujo","sequence":"additional","affiliation":[{"name":"Institute for Health Sciences, Federal University of Bahia, Salvador, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J F","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Institute for Health Sciences, Federal University of Bahia, Salvador, Brazil"},{"name":"Rheumatology Division, Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,1,4]]},"reference":[{"key":"bibr1-0961203317751063","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.287.6399.1088"},{"key":"bibr2-0961203317751063","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keg080"},{"key":"bibr3-0961203317751063","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2010.02263.x"},{"key":"bibr4-0961203317751063","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2010.05.004"},{"key":"bibr5-0961203317751063","doi-asserted-by":"publisher","DOI":"10.1002\/art.10187"},{"key":"bibr6-0961203317751063","doi-asserted-by":"publisher","DOI":"10.1177\/039463200601900421"},{"key":"bibr7-0961203317751063","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199907)42:7<1309::AID-ANR1>3.0.CO;2-F"},{"key":"bibr8-0961203317751063","unstructured":"The IDF consensus worldwide definition of the metabolic syndrome. 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