{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:59:53Z","timestamp":1790225993775,"version":"4.1.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>\n                    Primary Sj\u00f6gren's syndrome (pSS) is a systemic autoimmune disorder characterized by focal lymphocytic infiltration of the exocrine glands causing dry eyes and dry mouth. Similar glandular features can also occur as a late complication in patients with other rheumatic disorders, such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and scleroderma (\u2018secondary\u2019 Sj\u00f6gren's syndrome).\n                    <jats:sup>1<\/jats:sup>\n                  <\/jats:p>\n                  <jats:p>Anti-Ro and\/or anti-La (ENA) antibodies are found in approximately 70% of pSS patients, generally with ANA positivity. Hypergammaglobulinaemia is also common. Systemic features also occur in some patients with pSS. A positive rheumatoid factor (RF) is often seen and so if patients present with arthritis, dryness and a positive RF a diagnosis of pSS should be considered as a possible alternative to RA. Anti-CCP antibodies are more specific for RA.<\/jats:p>","DOI":"10.1177\/0961203318801673","type":"journal-article","created":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T12:04:24Z","timestamp":1542629064000},"page":"32-35","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":110,"title":["Primary Sj\u00f6gren's syndrome"],"prefix":"10.1177","volume":"27","author":[{"given":"SJ","family":"Bowman","sequence":"first","affiliation":[{"name":"Rheumatology Department, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,11,19]]},"reference":[{"key":"bibr1-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.47"},{"key":"bibr2-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-206860"},{"key":"bibr3-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.6.554"},{"key":"bibr4-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210571"},{"key":"bibr5-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.143743"},{"key":"bibr6-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.110619"},{"key":"bibr7-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kev385"},{"key":"bibr8-0961203318801673","doi-asserted-by":"crossref","unstructured":"Fisher BA, Jonsson R, Daniels T on behalf of the Sj\u00f6gren\u2019s histopathology workshop group (appendix) from ESSENTIAL (EULAR Sj\u00f6gren\u2019s syndrome study group),\n                      et al\n                      . Standardisation of labial salivary gland histopathology in clinical trials in primary Sj\u00f6gren\u2019s syndrome.\n                      Annals of the Rheumatic Diseases\n                      2017; 76: 1161\u20131168.","DOI":"10.1136\/annrheumdis-2016-210448"},{"key":"bibr9-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-203305"},{"key":"bibr10-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60720-0"},{"key":"bibr11-0961203318801673","doi-asserted-by":"crossref","unstructured":"Bowman S, Barone F. Biologic treatments in Sj\u00f6gren\u2019s syndrome.\n                      Presse Med\n                      2012; 41: e495\u2013509. http:\/\/dx.doi.org\/10.1016\/j. lpm.2012.05.024.","DOI":"10.1016\/j.lpm.2012.05.024"},{"key":"bibr12-0961203318801673","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.03.004"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0961203318801673","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0961203318801673","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0961203318801673","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:20:08Z","timestamp":1777677608000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0961203318801673"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":12,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1177\/0961203318801673"],"URL":"https:\/\/doi.org\/10.1177\/0961203318801673","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}