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Antiphospholipid syndrome (APS; Hughes syndrome) is characterized by the presence of antiphospholipid antibodies associated with thrombosis (arterial and\/or venous) and\/or pregnancy morbidity and could be the cause of MINOCA. Data on genetic predisposition to APS are scarce. The present study describes a unique case of monozygotic twin brothers who, at a young age, developed the same clinical presentation of APS. The diagnosis of APS was later confirmed, along with a diagnosis of systemic lupus erythematosus in one brother.<\/jats:p>","DOI":"10.1177\/0961203320906267","type":"journal-article","created":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T00:40:33Z","timestamp":1581381633000},"page":"505-508","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Double trouble: myocardial infarction with non-obstructive coronary arteries as a presentation of Hughes syndrome in monozygotic twins"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6094-7306","authenticated-orcid":false,"given":"A","family":"Djokovic","sequence":"first","affiliation":[{"name":"Department of Cardiology, Division of Interventional Cardiology, University Hospital Medical Centre Bezanijska kosa, Belgrade, Serbia"},{"name":"Faculty of Medicine, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Stojanovich","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University Hospital Medical Center Bezanijska kosa, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Stanisavljevic","sequence":"additional","affiliation":[{"name":"Department of Haematology, University Hospital Medical Center Bezanijska kosa, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Popovic","sequence":"additional","affiliation":[{"name":"Department of Radiology, CMR Lab, University Hospital Medical Center Bezanijska kosa, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Zdravkovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, Belgrade, Serbia"},{"name":"Department of Cardiology, CMR Lab, University Hospital Medical Center Bezanijska kosa, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,2,10]]},"reference":[{"key":"bibr1-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2016.04.002"},{"key":"bibr2-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1177\/0961203313520061"},{"key":"bibr3-0961203320906267","first-page":"756","volume":"31","author":"Stojanovich L","year":"2013","journal-title":"Clin Exp Rheumatol"},{"key":"bibr4-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2016.01.005"},{"key":"bibr5-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.011201"},{"key":"bibr6-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2009.03555.x"},{"key":"bibr7-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01753.x"},{"key":"bibr8-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"bibr9-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1980.tb03814.x"},{"key":"bibr10-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1177\/0961203312467393"},{"key":"bibr11-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy462"},{"key":"bibr12-0961203320906267","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.009174"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0961203320906267","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0961203320906267","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0961203320906267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:21:53Z","timestamp":1777677713000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0961203320906267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,10]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1177\/0961203320906267"],"URL":"https:\/\/doi.org\/10.1177\/0961203320906267","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,10]]}}}