{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T04:51:50Z","timestamp":1778907110023,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2020,9,13]],"date-time":"2020-09-13T00:00:00Z","timestamp":1599955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Juvenile systemic lupus erythematosus (JSLE) is usually associated with vitamin D deficiency and low bone mineral density.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate serum levels of 25-OH vitamin D in JSLE patients and to correlate these findings with disease activity and bone density.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was conducted on 100 patients with JSLE and 100 healthy children as controls. Disease duration and SLEDAI for disease activity were evaluated. CBC, anti-dsDNA, C3,C4,24hr urinary proteins, creatinine, estimated glomerular filtration rate(e-GFR),Ca,P,PTH, 25 (OH) D levels, and bone mineral density(BMD)Z score were measured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were significant differences in mean 25(OH)D concentration between patients group (19.37\u2009\u00b1\u20099.72\u2009ng\/ml) and controls 35.90\u2009\u00b1\u20099.66\u2009ng\/ml(p\u2009&lt;\u20090.05), with significant difference between active and inactive patients (p\u2009&lt;\u20090.05).There were significant negative correlations between serum 25(OH)D and SLEDAI (r-0.545, p 0.001), steroid dose (r-0.561, p 0.001), anti-dsDNA (r-0.685, p 0.006), 24\u2009hr-proteinuria (r-0.738, p 0.001) and PTH (r-0.335, p 0.001), significant positive correlations between 25(OH)D and C3 (r0.617, p 0.001),C4 (r0.544, p 0.001) serum Ca (r0.424, p 0.001) and Z score (r0.561, p 0.001),with non-significant correlations between 25(OH)D and serum P and both disease &amp; steroid duration, (p\u2009&gt;\u20090.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Vitamin D deficiency is common in JSLE, it\u2019s correlated significantly with disease activity and bone mineral density.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0961203320957721","type":"journal-article","created":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T02:16:53Z","timestamp":1600049813000},"page":"1752-1758","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Juvenile lupus and serum vitamin D levels: A cross-sectional study"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6414-5602","authenticated-orcid":false,"given":"Samar abd Alhamed","family":"Tabra","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Tanta University, Tanta, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hend Hassan","family":"Abdelnabi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tanta University, Tanta, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nivine Fathi Mahmoud","family":"Darwish","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tanta University, Tanta, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amal Mohammed","family":"El-Barbary","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tanta University, Tanta, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Tarek","family":"AbdelGhafar","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tanta University, Tanta, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Hassan","family":"Abu-Zaid","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Tanta University, Tanta, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,9,13]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2012.03.007"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13317-017-0101-x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-014-0228-x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2007.12.001"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/0961203314540966"},{"key":"e_1_3_2_7_2","first-page":"121","article-title":"Current daily glucocorticoid use and serum creatinine levels are associated with lower 25(OH) vitamin D levels in Thai patients with systemic lupus erythematosus","volume":"19","author":"Chaiamnuay S","year":"2013","unstructured":"Chaiamnuay S, Chailurkit L, Narongroeknawin P, Asavatanabodee P, Laohajaroensombat S, Chaiamnuay P. 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