{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T07:10:39Z","timestamp":1778569839465,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T00:00:00Z","timestamp":1674000000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To study the relationship between the 2019 EULAR\/ACR classification criteria and organ damage in patients with systemic lupus erythematosus (SLE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients involved in a cross-sectional validation study of the EULAR\/ACR criteria and judged by a panel of rheumatologists to be clinical SLE were studied. Those who fulfilled the EULAR\/ACR criteria at their last clinic visit were stratified into 2 groups based on a cutoff score of 20. The last SLE International Collaborating Clinic (SLICC) Organ Damage Index (SDI) was compared between these two groups. Relationship among the domains of the EULAR\/ACR criteria and SDI in all patients was studied by using Spearman\u2019s rank correlation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 562 SLE patients were studied (93.6% women; age 36.5 \u00b1 14.1\u00a0years; follow-up duration 11.6 \u00b1 6.6\u00a0years). The mean and median EULAR\/ACR criteria scores in those who fulfilled the EULAR\/ACR criteria ( N = 542) were 24.6 \u00b1 7.3 and 24 (interquartile range 19\u201330), respectively. A total of 392 patients had EULAR\/ACR scores of \u226520 (group 1), and 150 patients had scores of 10\u201319 (group 2). Group 1 patients had significantly higher prevalence of fever, alopecia, oral ulcers, acute lupus skin lesions, arthritis, serositis, seizure, hemolytic anemia, leukopenia, and renal disease and so were the anti-dsDNA, anti-Sm, antiphospholipid antibodies, and low complement state. Organ damage (SDI score of \u22651) occurred in 232 (42.8%) patients. Patients in group 1 had significantly higher SDI scores in the renal, cardiovascular, dermatological, and gonadal domains than group 2. The renal, neuropsychiatric, and antiphospholipid antibody domain scores of the EULAR\/ACR criteria correlated positively with the total SDI. The renal domain of the EULAR\/ACR criteria had the strongest correlation with renal damage (Rho 0.30; p &lt; 0.001). Patients who scored 10 points in the renal domain had significantly higher renal damage score than those scored 8 points or 4 points. Gonadal damage score was also significantly more common in the 10-point than in the 8-point group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In addition to disease classification, the EULAR\/ACR SLE criteria may have value in predicting prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09612033231153791","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T06:30:24Z","timestamp":1674023424000},"page":"424-430","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Relationship between the EULAR\/ACR classification criteria and organ damage in systemic lupus erythematosus"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3696-1228","authenticated-orcid":false,"given":"Chi Chiu","family":"Mok","sequence":"first","affiliation":[{"name":"Departments of Medicine, Tuen Mun Hospital, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuen Kwan","family":"Chung","sequence":"additional","affiliation":[{"name":"Departments of Medicine, Pok Oi Hospital, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn","family":"Lee","sequence":"additional","affiliation":[{"name":"Departments of Medicine, Pok Oi Hospital, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling Yin","family":"Ho","sequence":"additional","affiliation":[{"name":"Departments of Medicine, Tuen Mun Hospital, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi Hung","family":"To","sequence":"additional","affiliation":[{"name":"Departments of Medicine, Pok Oi Hospital, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,1,18]]},"reference":[{"key":"bibr1-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2018-214819"},{"key":"bibr2-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X221100300"},{"key":"bibr3-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24061"},{"key":"bibr4-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-021-05989-w"},{"key":"bibr5-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1177\/09612033211054397"},{"key":"bibr6-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2020-218670"},{"key":"bibr7-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780390303"},{"key":"bibr8-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24213"},{"key":"bibr9-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"bibr10-09612033231153791","doi-asserted-by":"publisher","DOI":"10.1002\/art.34473"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09612033231153791","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09612033231153791","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09612033231153791","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:26:39Z","timestamp":1777677999000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09612033231153791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,18]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1177\/09612033231153791"],"URL":"https:\/\/doi.org\/10.1177\/09612033231153791","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,18]]}}}