{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:11:11Z","timestamp":1777929071142,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate adverse pregnancy outcomes in patients with systemic lupus erythematosus (SLE), compare their maternal and fetal outcomes with those of age-matched pregnant women without SLE, and identify factors linked to increased risks of adverse outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Medical records from Tawam Hospital were reviewed retrospectively to identify patients with SLE and a history of pregnancy. Demographics, clinical variables, and maternal and fetal outcomes were obtained. A one-to-one age-matched healthy control group was randomly selected. The outcomes and odd ratios of women with and without SLE were compared, and factors associated with adverse pregnancy outcomes were examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The outcomes of 78 SLE pregnancies in 39 women were analyzed. Adverse maternal outcomes, such as gestational diabetes mellitus (GDM), occurred in 32% of pregnancies, whereas adverse fetal outcomes, such as low-birth weight and preterm deliveries, occurred in 51% of pregnancies. Pregnant women with SLE had a 5-fold higher risk of GDM, had higher odds of maternal hypertension, and were more likely to deliver through cesarean section than those without SLE. Preterm deliveries and low-birth weight were also more common in SLE pregnancies. Steroid use during pregnancy was significantly associated with an increased risk of GDM development. Lupus nephritis, maternal hypertension, pre-eclampsia, and GDM were linked to preterm deliveries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pregnant women with SLE were at a higher risk for adverse maternal and fetal outcomes than age-matched pregnant women without SLE. These findings can guide clinical management and emphasize the need for close monitoring of SLE pregnancies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09612033231204650","type":"journal-article","created":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T02:14:45Z","timestamp":1696299285000},"page":"1453-1461","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Maternal and fetal health outcomes in systemic lupus erythematosus pregnancies in the Emirati population: A comparative study"],"prefix":"10.1177","volume":"32","author":[{"given":"Hiba I","family":"Khogali","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Tawam Hospital, Al Ain, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghada S M","family":"Al\u2010Bluwi","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, College of Medicine & Health Sciences, UAE University, Al Ain, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virgie","family":"Guy Pedo","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, College of Medicine & Health Sciences, UAE University, Al Ain, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3005-2955","authenticated-orcid":false,"given":"Ali M","family":"Al Dhanhani","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, College of Medicine & Health Sciences, UAE University, Al Ain, 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