{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:12:55Z","timestamp":1777929175566,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T00:00:00Z","timestamp":1699488000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>\n                    Cranial neuropathy is a rare presentation in juvenile (j) SLE and being multiple is even rarer. We describe here an adolescent girl presenting with polyneuritis cranialis (PNC) as an initial presentation of SLE which had not been reported before in literature. She presented with symptoms suggestive of bilateral abducent and hypoglossal neuropathy with nerve conduction studies showing partial axonal neuropathy of left facial and accessory nerves, 6\u00a0weeks after common cold. The condition was not associated with any other neurological or systemic manifestations nor features of Sjogren\u2019s syndrome. Her condition responded well to pulsed methylprednisolone therapy and plasma exchange. After exclusion of the common causes and owing to the initial positive ANA results and mild proteinuria, renal biopsy was taken and revealed histopathological features of class III lupus nephritis for which mycophenolate mofetil was started at 1200\u00a0mg per m\n                    <jats:sup>2<\/jats:sup>\n                    . Our case highlights the importance of considering collagen disorders including SLE in the differential diagnosis of children presenting with PNC in order to allow adequate management and proper follow-up.\n                  <\/jats:p>","DOI":"10.1177\/09612033231215152","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T23:48:51Z","timestamp":1699573731000},"page":"1686-1688","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Polyneuritis cranialis as a unique initial presentation of juvenile systemic lupus erythematosus: Case report"],"prefix":"10.1177","volume":"32","author":[{"given":"Hoda","family":"Tomoum","sequence":"first","affiliation":[{"name":"Pediatric Neurology Unit, Children\u2019s Hospital, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5609-4160","authenticated-orcid":false,"given":"Rasha","family":"El-Owaidy","sequence":"additional","affiliation":[{"name":"Pediatric Allergy, Immunology and Rheumatology Unit, Children\u2019s Hospital, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abeer","family":"El-Zohiery","sequence":"additional","affiliation":[{"name":"Physical Medicine and Rehabilitation Department, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,11,9]]},"reference":[{"key":"bibr1-09612033231215152","first-page":"295","volume-title":"Textbook of Pediatric Rheumatology","author":"Klein-Gitelman MS","year":"2021","edition":"8"},{"key":"bibr2-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2023.105559"},{"key":"bibr3-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1177\/09612033211045050"},{"key":"bibr4-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1124023"},{"key":"bibr5-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-015-7678-7"},{"key":"bibr6-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2011.04.001"},{"key":"bibr7-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.11.1714"},{"key":"bibr8-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4156781"},{"key":"bibr9-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2016.01.003"},{"key":"bibr10-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2014.04.004"},{"key":"bibr11-09612033231215152","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-211898"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09612033231215152","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09612033231215152","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09612033231215152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:27:24Z","timestamp":1777678044000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09612033231215152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,9]]},"references-count":11,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1177\/09612033231215152"],"URL":"https:\/\/doi.org\/10.1177\/09612033231215152","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,9]]}}}