{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:30:34Z","timestamp":1788211834998,"version":"build-2803163510"},"reference-count":26,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T00:00:00Z","timestamp":1709856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with a history of adverse childhood experiences (ACEs) have a higher incidence of developing autoimmune diseases such as systemic lupus erythematosus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective is to associate the ACE with the clinical manifestations of SLE in adult women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a cross-sectional observational analytical study in a sample of women diagnosed with SLE, whose data were collected through interviews and a review of medical records. The ACE were identified using the Childhood Trauma Questionnaire (CTQ) and were associated with sociodemographic and clinical data, as well as the presence of harm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The sample was composed of 97 women. In this study, significant associations were found between physical abuse and oral ulcers ( p = .006) and nephritis ( p = .032); between sexual abuse and Sjogren\u2019s syndrome ( p = .024) and oral ulcers ( p = .035); between physical neglect and photosensitivity ( p = .024) and oral ulcers ( p = .039); and between emotional neglect and diabetes mellitus ( p = .033).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Individuals with a positive history of ACE have significant associations with certain clinical manifestations of SLE and subtypes of ACE, underscoring the importance of preventing childhood trauma to improve adult health. Further studies are needed to elucidate the impact of ACE on adult health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09612033241238056","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T17:59:01Z","timestamp":1709920741000},"page":"511-519","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Childhood adverse experiences and clinical manifestations in women with systemic lupus erythematosus"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7366-2089","authenticated-orcid":false,"given":"Elisa","family":"Esteves Rossini","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Federal University of Alagoas, Maceio, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7383-248X","authenticated-orcid":false,"given":"Jonatas","family":"Lourival Zanoveli Cunha","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Federal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1313-0919","authenticated-orcid":false,"given":"Gabriela","family":"L B Costa","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, CESMAC University Center, Maceio, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4562-4269","authenticated-orcid":false,"given":"Karin","family":"Araujo Melo","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Federal University of Alagoas, Maceio, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8185-0079","authenticated-orcid":false,"given":"Jos\u00e9 Pedro","family":"Cassemiro Micheleto","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Federal University of Alagoas, Maceio, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9913-2684","authenticated-orcid":false,"given":"Vanessa","family":"Miranda Pereira Fausto","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Federal University of Alagoas, Maceio, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2355-0799","authenticated-orcid":false,"given":"La\u00eds","family":"Quintiliano Pedroza","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Federal University of Alagoas, Maceio, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0192-0760","authenticated-orcid":false,"given":"Thiago","family":"Sotero Fragoso","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University Hospital Prof. Alberto Antunes, Maceio, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5914-0142","authenticated-orcid":false,"given":"Valfrido","family":"Le\u00e3o de Melo Neto","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University Hospital Prof. Alberto Antunes, Maceio, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4554-467X","authenticated-orcid":false,"given":"Michelle Jacintha","family":"Cavalcante Oliveira","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Federal University of Alagoas, Maceio, Brazil"},{"name":"Department of Medical Sciences, Federal University of Cear\u00e1, Fortaleza, Brazil; 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