{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:11:57Z","timestamp":1777929117937,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:p>Cytomegalovirus (CMV) infection and disease is a condition usually described in immunocompromised patients, but among them, those with connective tissue diseases are poorly represented. Here we present the clinical, laboratory characteristics, management and outcomes of systemic lupus erythematosus (SLE) patients who presented with a CMV infection\/disease to a high complexity hospital in southwestern Colombia between 2011 and 2020. 16 SLE patients were found to have a CMV infection. SLE was predominantly characterized by renal involvement (10 patients; 62.50%), and 14 patients (87.5%) were receiving steroids previous to the CMV infection. The entire sample required hospital admission, mainly related to acute kidney injury, and nine patients were admitted to the intensive care unit (ICU). Gastrointestinal organ damage was the most common CMV disease manifestation. All patients received ganciclovir, five of them (31.25%) suffered from septic shock, and seven (43.75%) died. Age \u226538\u00a0years and the presence of septic shock at admission were correlated to the mortality outcome. To our knowledge, this is the first publication evaluating SLE patients with CMV infection\/disease in a Colombian population.<\/jats:p>","DOI":"10.1177\/09612033241247103","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T11:49:32Z","timestamp":1714996172000},"page":"797-803","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Cytomegalovirus infection and disease in systemic lupus erythematosus patients at a high-complexity hospital in southwestern Colombia"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9633-6403","authenticated-orcid":false,"given":"Juan Fernando","family":"Contreras-Valero","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Pontificia Universidad Javeriana, Bogot\u00e1, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid","family":"Ru\u00edz-Ord\u00f3\u00f1ez","sequence":"additional","affiliation":[{"name":"GIRAT: Grupo de Investigaci\u00f3n en Reumatolog\u00eda, Inmunolog\u00eda y Medicina Traslacional, School of Medicine, Fundaci\u00f3n Valle del Lili, Universidad Icesi, Cali, Colombia"},{"name":"Facultad de Ciencias de la Salud, Universidad de Caldas, Manizales, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel D.","family":"Pinilla-Monsalve","sequence":"additional","affiliation":[{"name":"Centre de Recherche, Institut Universitaire de G\u00e9riatrie de Montr\u00e9al, Montr\u00e9al, QC, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Bautista-Vargas","sequence":"additional","affiliation":[{"name":"Unidad de Reumatolog\u00eda, Facultad de Ciencias de la Salud, Universidad Icesi, Cali, 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