{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:13:10Z","timestamp":1777929190035,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Societat Catalana de Reumatologia"},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine if there is a clinicodemographic or serological profile associated with MRI-confirmed inflammatory musculoskeletal abnormalities in SLE patients. To investigate the relationship between these alterations and HRQoL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>patients with SLE from our previous study in whom a wrist and hand MRI with contrast was performed were included. Sociodemographic, clinical, therapeutic, serological data and PROs were collected and correlated with MRI findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>83 patients were analysed. Erosions and synovitis were more common in older patients (55 \u00b1 12.61 vs 45.06 \u00b1 12.18\u00a0years, p .001, 52.78 \u00b1 12.99 vs 44.95 \u00b1 12.49\u00a0years, p .011). Synovitis was less frequent in patients with nephritis (6.7% vs 24.3%, p .031). Treatment received showed some associations: patients with bone edema received more methotrexate (25% vs 6.3%, p .033), those with erosions and peritendonitis received less mycophenolic acid (5.6% vs 22.9%, p .034; 0% vs 12.8%, p .026). Peritendonitis correlated with higher SLEDAI-2K (7 \u00b1 2.45 vs 3.64 \u00b1 3.34, p .018).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Worse HAQ<\/jats:title>\n                    <jats:p>Patients with synovitis, tenosynovitis, peritendonitis and bone edema reported higher pain (6.03 \u00b1 2.57 vs 4.26 \u00b1 2.49, p .005; 6.56 \u00b1 1.95 vs 4.76 \u00b1 2.75, p .017; 8.80 \u00b1 1.30 vs 4.95 \u00b1 2.55, p .001; 6.47 \u00b1 2.62 vs 4.83 \u00b1 2.58, p .026, respectively). Patients with synovitis reported higher fatigue numerical values (2.32 \u00b1 0.82 vs 1.91 \u00b1 0.84, p .035), with tenosynovitis worse FSS-9 (61.50 \u00b1 1.73 vs 45.70 \u00b1 16.80, p .015), and with both synovitis and peritendonitis worse HAQ (1.14 \u00b1 0.69 vs 0.75 \u00b1 0.65, p .031; 1.69 \u00b1 0.07 vs 0.90 \u00b1 0.69, p .018).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SLE patients with confirmed musculoskeletal alterations on MRI were generally older, less likely to have lupus nephritis, and received different treatments. They reported a worse HRQoL in terms of pain, fatigue and functional disability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09612033241301515","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T10:48:10Z","timestamp":1732099690000},"page":"10-17","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["SLE inflammatory musculoskeletal abnormalities, confirmed by MRI, show a specific profile with a worse health-related quality of life"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0970-0631","authenticated-orcid":false,"given":"Patricia","family":"Corzo","sequence":"first","affiliation":[{"name":"Rheumatology Department, Hospital Cl\u00ednic de Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Agust\u00ed Claramunt","sequence":"additional","affiliation":[{"name":"Musculoskeletal Radiology Department, Hospital del Mar-Parc de Salut Mar, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Garcia-Duitama","sequence":"additional","affiliation":[{"name":"Musculoskeletal Radiology Department, Hospital QuironSalud, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Carri\u00f3n-Barber\u00e1","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital del Mar-Parc de Salut Mar, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Marsico","sequence":"additional","affiliation":[{"name":"Musculoskeletal Radiology Department, Hospital del Mar-Parc de Salut Mar, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Duran Jord\u00e0","sequence":"additional","affiliation":[{"name":"AMIB - Assessoria Metodol\u00f2gica i Bioestad\u00edstica, IMIM, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordi","family":"Monfort Faure","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital del Mar-Parc de Salut Mar, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarek-Carlos","family":"Salman-Monte","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital del Mar-Parc de Salut Mar, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,11,20]]},"reference":[{"key":"bibr1-09612033241301515","unstructured":"Khamashta M, Vilardell M. 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