{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:23:57Z","timestamp":1788971037857,"version":"build-2803163510"},"reference-count":34,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T00:00:00Z","timestamp":1748563200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Systemic lupus erythematosus (SLE) primarily affects women of reproductive age. In pregnant women, frequent antepartum and intrapartum monitoring is required to improve obstetric outcomes and reduce the risk of flares. This study describes the characteristics of pregnant women with SLE and their obstetric and disease outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective descriptive cohort in a hospital in Bogot\u00e1, Colombia, from 1\/January\/2012 to 29\/February\/2024. The research was approved by the Ethics Committee. Descriptive statistics and univariate analysis by Fisher and Mann-Whitney U test were used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We analyzed 29 pregnancies of 28 women with a median age of 28\u00a0years, high educational and socioeconomic level, belonging to the social security system, and residing in Bogot\u00e1. Most of them had been diagnosed with SLE before pregnancy (median disease duration of 60\u00a0months). Twenty percent had poly-autoimmunity. Overall disease activity was mild to moderate. Obstetric outcomes (e.g. preterm delivery) were associated with a moderate to severe SLEPDAI (Systemic Lupus Erythematosus Pregnancy Disease Activity Index) score in the second and third trimester (83%,\n                      <jats:italic>p<\/jats:italic>\n                      = .04), shorter disease duration (24 vs 96\u00a0months,\n                      <jats:italic>p<\/jats:italic>\n                      = .027) and proteinuria &gt;1\u00a0g (40.91%,\n                      <jats:italic>p<\/jats:italic>\n                      = .03).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study associates preterm delivery with factors such as proteinuria &gt;1\u00a0g, shorter disease duration, and a moderate to severe score in the second trimester of pregnancy. A higher level of evidence is required to establish these associations with the causality of adverse outcomes in the Latin American population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09612033251345648","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T05:19:50Z","timestamp":1748582390000},"page":"864-873","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Maternal and fetal outcomes in pregnant patients with systemic lupus erythematosus: A study from a Latin American developing country"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3108-3203","authenticated-orcid":false,"given":"Juan Esteban","family":"Bedoya-Loaiza","sequence":"first","affiliation":[{"name":"Rheumatology, Fundaci\u00f3n Universitaria de Ciencias de la Salud (FUCS)- Hospital de San Jos\u00e9, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4408-3253","authenticated-orcid":false,"given":"Catalina","family":"Sanmiguel-Reyes","sequence":"additional","affiliation":[{"name":"Rheumatology, Fundaci\u00f3n Universitaria de Ciencias de la Salud (FUCS)- Hospital de San Jos\u00e9, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6063-277X","authenticated-orcid":false,"given":"Claudia","family":"Ib\u00e1\u00f1ez-Antequera","sequence":"additional","affiliation":[{"name":"Vice-Rectory of Research, Fundaci\u00f3n Universitaria de Ciencias de la Salud (FUCS), Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Escobar","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Fundaci\u00f3n Universitaria de Ciencias de la Salud (FUCS)- Hospital de San Jos\u00e9, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3145-2440","authenticated-orcid":false,"given":"Adriana","family":"Rojas-Villarraga","sequence":"additional","affiliation":[{"name":"Research Institute, Fundaci\u00f3n Universitaria de Ciencias de la Salud (FUCS), Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0468-4908","authenticated-orcid":false,"given":"Jairo","family":"Cajamarca-Bar\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Fundaci\u00f3n Universitaria de Ciencias de la Salud (FUCS)- Hospital de San Jos\u00e9, Bogot\u00e1, Colombia"},{"name":"Research Institute, Fundaci\u00f3n Universitaria de Ciencias de la Salud (FUCS), Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,30]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2018.11.001"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.39"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2018.1494239"},{"key":"e_1_3_4_5_2","first-page":"245","article-title":"Prevalencia de la enfermedad reum\u00e1tica en Colombia, seg\u00fan estrategia COPCORD-Asociaci\u00f3n Colombiana de Reumatolog\u00eda. Estudio de prevalencia de enfermedad reum\u00e1tica en poblaci\u00f3n colombiana mayor de 18 a\u00f1os","volume":"25","author":"Londo\u00f1o J","year":"2018","unstructured":"Londo\u00f1o J, Pel\u00e1ez Ballestas I, Cuervo F, et al. Prevalencia de la enfermedad reum\u00e1tica en Colombia, seg\u00fan estrategia COPCORD-Asociaci\u00f3n Colombiana de Reumatolog\u00eda. Estudio de prevalencia de enfermedad reum\u00e1tica en poblaci\u00f3n colombiana mayor de 18 a\u00f1os. 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Fetal and fetal and maternal outcomes of planned pregnancy in patients with systemic lupus erythematosus: A retrospective multicenter studyaternal outcomes of planned pregnancy in patients with systemic lupus erythematosus: a retrospective multicenter study. 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