{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:09:57Z","timestamp":1790161797337,"version":"4.1.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T00:00:00Z","timestamp":1786838400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lupus"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease associated with impaired health-related quality of life (HRQoL). The LupusQoL is a disease-specific instrument designed to capture SLE-related HRQoL domains; however, a validated Arabic version remains unavailable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the reliability and validity of the Arabic version of LupusQoL (Ar-LupusQoL) in SLE Egyptian patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this multicenter cross-sectional study, 156 patients with SLE completed the Arabic LupusQoL and Short Form-36 (SF-36). Disease activity and damage were assessed using Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) and Systemic Lupus International Collaborating Clinics\/American College of Rheumatology Damage Index (SLICC\/ACR-DI), respectively. Internal consistency was assessed using Cronbach\u2019s alpha, and test\u2013retest reliability using intraclass correlation coefficients. Construct validity was examined through item\u2013total correlations and correlations with corresponding SF-36 domains. Discriminant validity was also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age was 33.37 \u00b1 10.71\u00a0years, and 98.1% were female. The cohort demonstrated a high level of disease activity (87.2% with SLEDAI &gt;4; mean SLEDAI 19.52 \u00b1 16.20). Internal consistency was high across domains (\u03b1 = 0.78\u20130.98). Item\u2013total correlations were strong (r &gt; 0.30,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Significant correlations with corresponding SF-36 domains supported convergent validity (r = 0.668\u20130.829, p &lt; 0.05). The Ar-LupusQoL effectively discriminated between active and inactive disease (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Ceiling effects were observed in selected domains, with no significant floor effects.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The Arabic version of the LupusQoL is a reliable and valid instrument for assessing HRQoL in Egyptian patients with SLE. The high disease activity observed, likely reflecting recruitment from tertiary referral centers, may limit generalizability to patients with milder disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09612033261477825","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T01:20:05Z","timestamp":1786929605000},"page":"1407-1414","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychometric validation and reliability of the Arabic version of the LupusQoL questionnaire (Ar-LupusQoL) in Egyptian patients with systemic lupus erythematosus"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3392-6603","authenticated-orcid":false,"given":"Omima Ahmed","family":"El-Farra","sequence":"first","affiliation":[{"name":"Minia University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmeen Abdelhakim","family":"Abdelnaby","sequence":"additional","affiliation":[{"name":"Minia University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8914-0791","authenticated-orcid":false,"given":"Ahmed Adel","family":"Abdel Azim","sequence":"additional","affiliation":[{"name":"Assiut University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6777-1973","authenticated-orcid":false,"given":"Gamal Saeed","family":"Gamal","sequence":"additional","affiliation":[{"name":"Zagazig University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4995-6015","authenticated-orcid":false,"given":"Amal Mohamed","family":"Elmesiry","sequence":"additional","affiliation":[{"name":"Faculty of Medicine for girls Al-Azhar University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nermeen Mohammed","family":"Elmenayar","sequence":"additional","affiliation":[{"name":"Mansoura University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9896-9028","authenticated-orcid":false,"given":"Shereen R.","family":"Kamel","sequence":"additional","affiliation":[{"name":"Minia University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manal","family":"Hassanien","sequence":"additional","affiliation":[{"name":"Assiut University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaimaa Moustafa","family":"Hafez","sequence":"additional","affiliation":[{"name":"Minia University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wedad Mahmoud","family":"Ghazy","sequence":"additional","affiliation":[{"name":"Zagazig University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,16]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-13071-7"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-211663"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/lupus-2025-001671"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24245"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40271-023-00670-7"},{"key":"e_1_3_8_7_2","first-page":"1706","article-title":"How does quality of life of patients with systemic lupus erythematosus compare with that of other common chronic illnesses?","volume":"32","author":"Jolly M","year":"2005","unstructured":"Jolly M. How does quality of life of patients with systemic lupus erythematosus compare with that of other common chronic illnesses? J Rheumatol 2005; 32: 1706\u20131708.","journal-title":"J Rheumatol"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.110007"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-010-0110-5"},{"key":"e_1_3_8_10_2","doi-asserted-by":"crossref","first-page":"S413","DOI":"10.1002\/acr.20636","article-title":"Health-related quality of life measurement in adult systemic lupus erythematosus: Lupus Quality of Life (LupusQoL), Systemic Lupus Erythematosus-Specific Quality of Life Questionnaire (SLEQOL), and Systemic Lupus Erythematosus Quality of Life Questionnai\u2026","volume":"63","author":"Yazdany J","year":"2011","unstructured":"Yazdany J. Health-related quality of life measurement in adult systemic lupus erythematosus: Lupus Quality of Life (LupusQoL), Systemic Lupus Erythematosus-Specific Quality of Life Questionnaire (SLEQOL), and Systemic Lupus Erythematosus Quality of Life Questionnai\u2026. Arthritis Care Res 2011; 63: S413\u2013S419.","journal-title":"Arthritis Care Res"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.22881"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/JOURNAL.PONE.0285461"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.reumae.2021.02.005"},{"key":"e_1_3_8_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/09612033251344995"},{"key":"e_1_3_8_15_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063795"},{"key":"e_1_3_8_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/0961203314565412"},{"key":"e_1_3_8_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.40930"},{"key":"e_1_3_8_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199803000-00018"},{"key":"e_1_3_8_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa051135"},{"key":"e_1_3_8_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780390303"},{"key":"e_1_3_8_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/S13075-020-2095-4"},{"key":"e_1_3_8_22_2","doi-asserted-by":"publisher","DOI":"10.1177\/0961203312456749"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09612033261477825","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09612033261477825","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09612033261477825","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T10:16:45Z","timestamp":1790158605000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09612033261477825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,16]]},"references-count":21,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1177\/09612033261477825"],"URL":"https:\/\/doi.org\/10.1177\/09612033261477825","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,16]]}}}