{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T11:52:04Z","timestamp":1790941924366,"version":"4.1.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1992,2,1]],"date-time":"1992-02-01T00:00:00Z","timestamp":696902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lupus"],"published-print":{"date-parts":[[1992,2]]},"abstract":"<jats:p>\n                    Anticardiolipin antibodies (aCL) purified from patients with autoimmune disease have recently been shown to interact with a phospholipid-binding plasma protein, \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -glycoprotein I (\u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -GPI). The aim of this study was to determine whether aCL purified from patients with infection also interact with \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -GPI.\n                  <\/jats:p>\n                  <jats:p>\n                    aCL purified from 23 patients with malaria, infectious mononucleosis, tuberculosis, hepatitis A or syphilis did not require the presence of \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -GPI to bind cardiolipin (CL). In contrast, aCL were purified from 11 out of 12 patients with autoimmune disease that bound CL only in the presence of \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -GPI. Thrombotic complications appear to be associated with aCL occurring in autoimmune disease but not with aCL associated with infections. We postulate that this increased risk of thrombosis in the autoimmune group may be due to the presence of aCL that bind CL in association with \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -GPI, a plasma protein with anticoagulant activity.\n                  <\/jats:p>","DOI":"10.1177\/096120339200100204","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T19:27:11Z","timestamp":1196105231000},"page":"75-81","source":"Crossref","is-referenced-by-count":206,"title":["A Phospholipid-\u03b22-Glycoprotein I Complex Is an Antigen for Anticardiolipin Antibodies Occurring in Autoimmune Disease But Not with Infection"],"prefix":"10.1177","volume":"1","author":[{"given":"John E.","family":"Hunt","sequence":"first","affiliation":[{"name":"University of New South Wales, School of Medicine, St George Hospital Kogarah, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Patrick","family":"McNeil","sequence":"additional","affiliation":[{"name":"University of New South Wales, School of Medicine, St George Hospital Kogarah, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary J.","family":"Morgan","sequence":"additional","affiliation":[{"name":"University of New South Wales, School of Medicine, St George Hospital Kogarah, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina M.","family":"Crameri","sequence":"additional","affiliation":[{"name":"University of New South Wales, School of Medicine, St George Hospital Kogarah, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Krilis","sequence":"additional","affiliation":[{"name":"University of New South Wales, School of Medicine, St George Hospital Kogarah, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1992,2,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-48-13365P"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1952.03680050033010"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)91658-9"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)91267-9"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830270408"},{"key":"atypb6","first-page":"557","volume":"69","author":"Manoussakis MN","year":"1987","journal-title":"Clin Exper Immunol"},{"key":"atypb7","first-page":"259","volume":"14","author":"Lockshin MD","year":"1987","journal-title":"J Rheumatol"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1985.tb02988.x"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-112-9-682"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/157.1.23"},{"key":"atypb11","first-page":"4120","volume":"199","author":"McNeil HP","journal-title":"Proc Natl Acad Sci USA"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)91697-9"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1136\/ard.46.1.1"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(88)90133-8"},{"key":"atypb15","first-page":"215","volume":"68","author":"Harris EN","year":"1987","journal-title":"Clin Exp Immunol"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(88)90136-3"},{"key":"atypb17","volume-title":"new radioimmunoassay for \u03b22-glycoprotein-I levels in plasma","author":"McNeil HP"},{"key":"atypb18","first-page":"363","volume":"251","author":"Thorell JI","year":"1971","journal-title":"Biochem Biophys Acta"},{"key":"atypb19","volume-title":"BCTIC Computer Code Collection (technical manual)","author":"Rodbard D.","year":"1984"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1989.tb00289.x"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)91374-J"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1016\/0020-711X(84)90168-X"},{"key":"atypb23","first-page":"1","volume":"16","author":"Harris EN","year":"1985","journal-title":"J Clin Lab Immunol"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)60777-4"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9150(87)90110-9"},{"key":"atypb26","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(86)90237-0"}],"container-title":["Lupus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096120339200100204","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096120339200100204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:30:04Z","timestamp":1777678204000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096120339200100204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,2]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,2]]}},"alternative-id":["10.1177\/096120339200100204"],"URL":"https:\/\/doi.org\/10.1177\/096120339200100204","relation":{},"ISSN":["0961-2033","1477-0962"],"issn-type":[{"value":"0961-2033","type":"print"},{"value":"1477-0962","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,2]]}}}