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Eight of the 18 scans were abnormal (44%), four in a diffuse bitemporo-parietal pattern previously noted only in Alzheimer's disease, and four with large focal deficits. Neither the existence of the abnormal scan nor the particular pattern of abnormality correlated with the results of other diagnostic tests. These preliminary results raise the possibility that SPECT scans may offer an additional valuable diagnostic instrument in CNS lupus, although further studies are necessary to delineate their precise role.<\/jats:p>","DOI":"10.1177\/096120339200100404","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T19:27:11Z","timestamp":1196105231000},"page":"215-219","source":"Crossref","is-referenced-by-count":24,"title":["I-123 Iofetamine SPECT Scan in Systemic Lupus Erythematosus Patients with Cognitive and Other Minor Neuropsychiatric Symptoms: A Pilot Study"],"prefix":"10.1177","volume":"1","author":[{"given":"Malcolm P.","family":"Rogers","sequence":"first","affiliation":[{"name":"Divisions of Psychiatry and Neurology, Departments of Medicine, Rheumatology and Immunology, and Radiology, Brigham and Women's Hospital, Harvard Medical School, Robert B. 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