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The second case is unusual in being resistant to immunosuppressive treatment. Bone marrow culture from the second patient revealed an inhibition of BFU-E colony formation in the presence of the patient's serum, indicating that a serum inhibitor of haemopoiesis was present. Furthermore, following T cell depletion of this patient's marrow, there was an increase in BFU-E, CFU-G and CFU-GM colony growth implicating, in addition, a possible T cell-mediated inhibition of marrow haemopoiesis. This is a novel observation and may explain the resistance shown by this patient to standard treatment.<\/jats:p>","DOI":"10.1177\/096120339500400512","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T19:27:11Z","timestamp":1196105231000},"page":"407-411","source":"Crossref","is-referenced-by-count":27,"title":["Erythrocyte aplasia and systemic lupus erythematosus"],"prefix":"10.1177","volume":"4","author":[{"given":"Pdw","family":"Kiely","sequence":"first","affiliation":[{"name":"Department of Rheumatology, St. George's Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CP","family":"McGuckin","sequence":"additional","affiliation":[{"name":"Department of Haematology, St. George's Hospital, London SW17 OQT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DA","family":"Collins","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, St. George's Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DH","family":"Bevan","sequence":"additional","affiliation":[{"name":"Department of Haematology, St. George's Hospital, London SW17 OQT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jcw","family":"Marsh","sequence":"additional","affiliation":[{"name":"Department of Haematology, St. George's Hospital, London SW17 OQT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1995,10,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(68)90059-4"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(76)90050-8"},{"key":"atypb3","doi-asserted-by":"crossref","unstructured":"Sutherland HJ, Eaves AC, Eaves CJ Quantitative assays for human hematopoietic progenitor cells. 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