{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T11:48:14Z","timestamp":1789818494226,"version":"4.0.1"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T00:00:00Z","timestamp":1475193600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Stat Methods Med Res"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:p>McNemar\u2019s test is often used in practice to compare the sensitivities and specificities for the evaluation of two diagnostic tests. For correct evaluation of accuracy, an intuitive recommendation is to test the diseased and the non-diseased groups separately so that the sensitivities can be compared among the diseased, and specificities can be compared among the healthy group of people. This paper provides a rigorous theoretical framework for this argument and study the validity of McNemar\u2019s test regardless of the conditional independence assumption. We derive McNemar\u2019s test statistic under the null hypothesis considering both assumptions of conditional independence and conditional dependence. We then perform power analyses to show how the result is affected by the amount of the conditional dependence under alternative hypothesis.<\/jats:p>","DOI":"10.1177\/0962280214541852","type":"journal-article","created":{"date-parts":[[2014,7,4]],"date-time":"2014-07-04T23:39:56Z","timestamp":1404517196000},"page":"142-154","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":107,"title":["Does McNemar\u2019s test compare the sensitivities and specificities of two diagnostic tests?"],"prefix":"10.1177","volume":"26","author":[{"given":"Soeun","family":"Kim","sequence":"first","affiliation":[{"name":"Division of Biostatistics, University of Texas Health Science Center, Houston, TX, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woojoo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Statistics, Inha University, Nam-gu, Incheon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,9,30]]},"reference":[{"key":"bibr1-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1007\/BF02295996"},{"key":"bibr2-0962280214541852","first-page":"582","volume":"178","author":"Mann FA","year":"1991","journal-title":"Radiology"},{"key":"bibr3-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.178.2.1987587"},{"key":"bibr4-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.70.832.9166071"},{"key":"bibr5-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1002\/sim.906"},{"key":"bibr6-0962280214541852","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1090"},{"key":"bibr7-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1080\/00365510701666031"},{"key":"bibr8-0962280214541852","doi-asserted-by":"publisher","DOI":"10.2307\/2530967"},{"key":"bibr9-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5877(00)00119-7"},{"key":"bibr10-0962280214541852","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2002.63.1598"},{"key":"bibr11-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1111\/j.0006-341X.2001.00158.x"},{"key":"bibr12-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(81)90059-X"},{"key":"bibr13-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir185"},{"key":"bibr14-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1111\/j.1863-2378.2009.01281.x"},{"key":"bibr15-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-007-0376-3"},{"key":"bibr16-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2010.00492.x"},{"key":"bibr17-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1159\/000196477"},{"key":"bibr18-0962280214541852","doi-asserted-by":"publisher","DOI":"10.2307\/2983604"},{"key":"bibr19-0962280214541852","doi-asserted-by":"publisher","DOI":"10.2307\/3283016"},{"key":"bibr20-0962280214541852","first-page":"795","volume":"41","author":"Smeeton NC","year":"1985","journal-title":"Biometrics"},{"key":"bibr21-0962280214541852","doi-asserted-by":"publisher","DOI":"10.1037\/h0026256"}],"container-title":["Statistical Methods in Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0962280214541852","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0962280214541852","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0962280214541852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:47:21Z","timestamp":1777679241000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0962280214541852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,30]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1177\/0962280214541852"],"URL":"https:\/\/doi.org\/10.1177\/0962280214541852","relation":{},"ISSN":["0962-2802","1477-0334"],"issn-type":[{"value":"0962-2802","type":"print"},{"value":"1477-0334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,30]]}}}