{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T06:05:19Z","timestamp":1784700319529,"version":"3.55.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T00:00:00Z","timestamp":1778457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acupunct Med"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Nausea, vomiting and pain are common postoperative complications. The aim of this study was to evaluate the effects of ondansetron combined with acupuncture at bilateral PC6 during the intraoperative period on the incidence of postoperative nausea and vomiting (PONV), severity of nausea\/pain and the need for rescue antiemetics in patients undergoing elective one- or two-level lumbar disc herniation (LDH) surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this double-blind randomized controlled trial, 92 patients with American Society of Anesthesiologists (ASA) physical status I\u2013II who were scheduled for elective LDH surgery under general anesthesia were randomized into two groups: the acupuncture group (group A) and the control group (group C). Group A received PC6 acupuncture bilaterally plus ondansetron; group C received ondansetron only. PONV was defined as nausea with a visual analog scale (VAS) score \u2a7e4, vomiting or need for rescue medication. Persistent nausea (&gt;20\u2009min), unchanged score or repeated vomiting prompted administration of 4\u2009mg intravenous (IV) ondansetron. Pain scores \u2a7e4 were treated with IV dexketoprofen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Data on 79 patients (n\u2009=\u200940 in group A and n\u2009=\u200939 in group C) were analyzed. The incidence of PONV within 24\u2009h (primary outcome) did not significantly differ in group A versus group C (15.0% vs 33.3%, p\u2009=\u20090.057). However, nausea incidence at 0\u201324\u2009h, as well as PONV incidence and rescue antiemetic use at 0\u20132\u2009h, were significantly lower in group A (p\u2009&lt;\u20090.05). Nausea and pain severity were also significantly lower in group A at 0\u20132 and 2\u20134\u2009h (p\u2009&lt;\u20090.05). A moderate positive correlation was found between pain and nausea severity over 24\u2009h (p\u2009&lt;\u20090.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Although this study was negative in its primary endpoint, multiple significant secondary findings suggest that acupuncture with standard antiemetic therapy was associated with lower early PONV and reduced rescue antiemetic use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number:<\/jats:title>\n                    <jats:p>NCT06669676 (ClinicalTrials.gov).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09645284261441885","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T09:16:08Z","timestamp":1778490968000},"page":"201-209","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of acupuncture on postoperative nausea and vomiting in lumbar disc herniation surgery"],"prefix":"10.1177","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6642-2279","authenticated-orcid":false,"given":"Gokhan","family":"Erdem","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Bilkent City Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma","family":"Kavak Akelma","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Bilkent City Hospital, Ankara, Turkey"},{"name":"Department of Anesthesiology and Reanimation, Faculty of Medicine, Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burak","family":"Nalbant","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Bilkent City Hospital, Ankara, Turkey"},{"name":"Department of Anesthesiology and Reanimation, Faculty of Medicine, Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nihal","family":"G\u00f6kbulut \u00d6zaslan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Bilkent City Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,11]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2019.02.012"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wnsx.2024.100276"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00064-016-0467-3"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-022-01943-8"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2012.62.6.543"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000006509"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-023-02091-3"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-021-01172-9"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004833"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/ANA.0000000000000936"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2010900"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000031478"},{"key":"e_1_3_2_14_2","first-page":"147","article-title":"Selection of acupoints for managing upper-extremity spasticity in chronic stroke","volume":"9","author":"Wang BH","year":"2014","unstructured":"Wang BH, Lin CL, Li TM, et al. Selection of acupoints for managing upper-extremity spasticity in chronic stroke. Clin Interv Aging 2014; 9: 147\u2013156.","journal-title":"Clin Interv Aging"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6619855"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181ff47e2"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000877"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2020.12.023"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocn.14705"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2021.06.015"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.4103\/sja.SJA_401_19"},{"issue":"5","key":"e_1_3_2_22_2","first-page":"441","article-title":"Effect of electroacupuncture at \u201cNeiguan\u201d (PC6) on pain and brain orexin 1 receptor in mice with inflammatory pain","volume":"49","author":"Ma NQ","year":"2024","unstructured":"Ma NQ, Yang JL, Shi JJ, et al. Effect of electroacupuncture at \u201cNeiguan\u201d (PC6) on pain and brain orexin 1 receptor in mice with inflammatory pain. Acupunct Res 2024; 49(5): 441\u2013447.","journal-title":"Acupunct Res"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-022-00797-7"},{"issue":"11","key":"e_1_3_2_24_2","article-title":"Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting","volume":"2015","author":"Lee A","year":"2015","unstructured":"Lee A, Chan SKC, Fan LTY. Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting. Cochrane Database Syst Rev 2015; 2015(11): CD003281.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/ueg2.12421"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aep014"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2012.12.025"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq406"},{"issue":"5","key":"e_1_3_2_29_2","article-title":"Recent advances in acupuncture for pain relief","volume":"9","author":"Niruthisard S","year":"2024","unstructured":"Niruthisard S, Ma Q, Napadow V. Recent advances in acupuncture for pain relief. 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