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Morphologic types of lesions have long since been studied in order to understand plaque evolution and determinants of plaque complication, a frequent cause of acute ischemic accidents. Chemical and pathophysiological studies defined the wide spectrum of molecular interactions between cellular elements of atherosclerotic lesions. Recently, molecular biologic investigations provide a deeper insight into genetic predispositions for the disease and have widened our understanding of the pathogenic mechanisms. Until we can diminish the high prevalence of the disease, precise information is needed on the evolution of atherosclerosis in order to slow progression, select optimal therapies and prevent plaque complications and their consequences. <\/jats:p>","DOI":"10.1177\/096721090100900201","type":"journal-article","created":{"date-parts":[[2024,9,22]],"date-time":"2024-09-22T09:13:09Z","timestamp":1726996389000},"page":"109-121","source":"Crossref","is-referenced-by-count":13,"title":["Development of Atherosclerosis and Plaque Biology"],"prefix":"10.1177","volume":"9","author":[{"given":"A.","family":"K\u00e1d\u00e1r","sequence":"first","affiliation":[{"name":"2nd Department of Pathology, Semmelweis University of Medicine, \u00dcll\u00f5i \u00fat 93, H-1091 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Glasz","sequence":"additional","affiliation":[{"name":"2nd Department of Pathology, Semmelweis University of Medicine, \u00dcll\u00f5i \u00fat 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